Kendall Lab

At the Kendall Lab, associated with the Department of Microbiology, Immunology, and Cancer Biology (MIC), we are interested in mechanisms that bacterial pathogens use to integrate host- and bacterial-derived signals to sense their environment, coordinate gene expression, and cause disease.

We study these processes in the intestinal pathogens enterohemorrhagic E. coli O157:H7, Salmonella enterica, and Citrobacter rodentium. Our projects involve a mix of experimental approaches, ranging from genetics, biochemistry, microscopy, and bioinformatics.

How Salmonella Defeats Immune System

In a surprising new discovery about potentially deadly salmonella, researchers have determined that the foodborne bacteria has a most unexpected way of telling where it is in the body: It uses its food as its GPS.

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EHEC adhering to epithelial cells

Salmonella Strategies for Host Adaptation

Understanding bacterial adaptation strategies helps us provide new therapeutic intervention strategies.

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cartoon explanation of digestion

‘Trail of Bread Crumbs’ Map for Pathogens

Microbiota release nutrients which provide spatial information to pathogens, giving them a map to the intestinal landscape.

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