We are in the Department of Microbiology, Immunology, and Cancer Biology at the University of Virginia. Broadly, we are interested in mechanisms that bacterial pathogens use to integrate host- and bacterial-derived signals to sense their environment, coordinate gene expression, and cause disease.
We study these processes in the intestinal pathogens enterohemorrhagic E. coli O157:H7, Salmonella enterica, and Citrobacter rodentium. Our projects involve a mix of experimental approaches, ranging from genetics, biochemistry, microscopy, and bioinformatics. Please explore our website to find out more about the lab’s ongoing research and the people doing the work.