Latest News

Laura A. Gonyar, Recipient of the 2015 Robert R. Wagner Prize

Laura A. Gonyar Ph.D. in Microbiology, December 2014 Kendall Laboratory Thesis:  Ethanolamine-regulated fimbriae in enterohemorrhagic Escherichia coli O157:H7 pathogenesis Research: Laura showed that ethanolamine (EA), which is abundant in the gastrointestinal tract, promoted the transcription of EHEC fimbriae, expression of fimbrial structures on the surface of bacterial cells, and early adherence to epithelial cells. These findings demonstrate that EHEC fimbriae are expressed in response … [Read more...]

M. Brittany Johnson, Recipient of the 2014 Wagner Prize

M. Brittany Johnson Ph.D. in Microbiology,  May 2014 Criss Lab Thesis: Mechanisms of Neisseria gonorrhoeae intracellular survival inside primary human neutrophils Research: Brittany’s thesis research focuses on mechanisms of Neisseria gonorrhoeae(Gc) survival inside primary human neutrophils. Gc is the causative agent of the major global health problem, gonorrhea. In response to infection with Gc abundant neutrophils are recruited. However, Gc can be cultured from patient exudates, … [Read more...]

Amelia E. Hufford, 2013 Wagner Prize Recipient

Amelia E. Hufford Ph.D. in Microbiology,  May 2013 Ravichandran Lab Thesis: "Phosphatidylserine recognition receptors: promoters of muscle development and apoptotic cell engulfment" Research In the laboratory of Dr. Kodi Ravichandran, Amelia’s thesis research focused on understanding the role of the phosphatidylserine (PtdSer) receptor, BAI1, and apoptotic cells in muscle development and repair. Myoblasts are muscle progenitor cells that must fuse with one another during muscle … [Read more...]

George W. Liechti Receives 2012 Wagner Prize

George W. Liechti Ph.D. in Microbiology, Fall 2012 Goldberg Lab Thesis: "Purine acquisition and biosynthesis in Helicobacter pylori" Research George works with the bacterium Helicobacter pylori, a causative agent of gastritis, duodenal ulceration, and gastric cancer. He is currently investigating the purine salvage pathway in H. pylori with the goal of fully elucidating the essential enzymes required for maintaining the bacterium’s nucleotide pool. Its inability to synthesize purines de … [Read more...]

Matthew T. Hufford, 2011 Recipient of the Wagner Prize

Matthew T. Hufford Ph.D. in Microbiology, Spring 2011 Braciale Lab Thesis: "Regulation of Cytotoxic T Lymphocytes Effector Function During Experimental Murine Influenza Infection" Research Matthew's thesis research focused on the regulation of cytotoxic T lymphocyte (CTL) effector function during murine influenza infection. He demonstrated that indeed CTLs could recognize infected respiratory epithelial cells and destroy the cells but that this T cell/target cell interaction did not lead … [Read more...]

Derek Dube, 2010 Recipient of the Wagner Prize

Derek Dube Ph.D. in Microbiology, Spring 2010 Judy White Lab Thesis: "Ebolavirus Entry: Cell adhesion-dependent control of viral tropism" Research In the laboratory of Dr. Judith White, Derek's work has focused on the initial stage of viral entry. Employing cell culture systems, Derek recognized a role for cellular adhesion in the regulation of ebolavirus tropism. He showed that cells that grow in suspension (including lymphocytes) formerly thought to lack an ebolavirus receptor actually … [Read more...]

Anna Maria Copeland, Recipient of the 2009 Wagner Prize

Anna Maria Copeland Ph.D. in Microbiology, May 2009 Jay Brown Lab Thesis: Herpes Simplex Virus Replication: Roles of Viral Proteins and Nucleoporins in Capsid-Nucleus Attachment. Research Replication of herpes simplex virus (HSV-1) involves a step in which a parental capsid docks onto a host nuclear pore complex (NPC). The viral genome then translocates through the nuclear pore into the nucleoplasm where it is transcribed and replicated to propagate infection. We have developed a live … [Read more...]