Ph.D. in Microbiology, Fall 2012
“Purine acquisition and biosynthesis in Helicobacter pylori“
George works with the bacterium Helicobacter pylori, a causative agent of gastritis, duodenal ulceration, and gastric cancer. He is currently investigating the purine salvage pathway in H. pylori with the goal of fully elucidating the essential enzymes required for maintaining the bacterium’s nucleotide pool. Its inability to synthesize purines de novomakes key enzymes in this pathway attractive drug targets for future antimicrobials.