George W. Liechti Receives 2012 Wagner Prize

George W. Liechti
Ph.D. in Microbiology, Fall 2012
Goldberg Lab

Thesis:
Purine acquisition and biosynthesis in Helicobacter pylori

Research
George works with the bacterium Helicobacter pylori, a causative agent of gastritis, duodenal ulceration, and gastric cancer. He is currently investigating the purine salvage pathway in H. pylori with the goal of fully elucidating the essential enzymes required for maintaining the bacterium’s nucleotide pool. Its inability to synthesize purines de novomakes key enzymes in this pathway attractive drug targets for future antimicrobials.