2019 MIC Student Publications

HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA.
Gray LR, Jackson RE, Jackson PEH, Bekiranov S, Rekosh D, Hammarskjöld ML.Retrovirology. 2019 Dec 16;16(1):40. doi: 10.1186/s12977-019-0505-y. PMID: 31842941; PMCID: PMC6916052

Ly49R activation receptor drives self-MHC-educated NK cell immunity against cytomegalovirus infection.
Gamache A, Cronk JM, Nash WT, Puchalski P, Gillespie A, Wei H, Gray L, Hammarskjold ML, Xu W, Brown MG. Proc Natl Acad Sci U S A. 2019 Dec 16;116(52):26768–78. doi: 10.1073/pnas.1913064117. Epub ahead of print. PMID: 31843910; PMCID: PMC6936569.

Natural selection for killer receptors and their MHC class I ligands: In pursuit of gene pairs that fit well in tandem.
Brown MG, Gamache A, Nash WT, Cronk J. J Leukoc Biol. 2019 Mar;105(3):489-495. doi: 10.1002/JLB.2RI0818-315R. Epub 2018 Nov 30. PMID: 30500089.

Type 3 Immunity during Clostridioides difficile Infection: Too Much of a Good Thing?
Saleh MM, Petri WA Jr. Infect Immun. 2019 Dec 17;88(1):e00306-19. doi: 10.1128/IAI.00306-19. PMID: 31570564; PMCID: PMC6921663.

IL-10 and ICOS Differentially Regulate T Cell Responses in the Brain during Chronic Toxoplasma gondii Infection.
O’Brien CA, Batista SJ, Still KM, Harris TH. J Immunol. 2019 Mar 15;202(6):1755-1766. doi: 10.4049/jimmunol.1801229. Epub 2019 Feb 4. PMID: 30718297; PMCID: PMC6401250

T cells in severe childhood asthma.
Paul AGA, Muehling LM, Eccles JD, Woodfolk JA. Clin Exp Allergy. 2019 May;49(5):564-581. doi: 10.1111/cea.13374. PMID: 30793397; PMCID: PMC6488378.

Models and molecular mechanisms of blood vessel co-option by cancer cells.
Zhang Y, Wang S, Dudley AC. Angiogenesis. 2019 Oct 18. doi: 10.1007/s10456-019-09684-y. [Epub ahead of print] Review. PMID: 31628560

Type 3 immunity during Clostridioides difficile infection: too much of a good thing?
Saleh MM, Petri WA Jr.
nfect Immun. 2019 Sep 30. pii: IAI.00306-19. doi: 10.1128/IAI.00306-19. [Epub ahead of print] Review.
PMID: 31570564

Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis.
Upadhye A, Srikakulapu P, Gonen A, Hendrikx S, Perry HM, Nguyen A, McSkimming C, Marshall MA, Garmey JC, Taylor AM, Bender TP, Tsimikas S, Holodick NE, Rothstein TL, Witztum JL, McNamara CA.
Circ Res. 2019 Oct 25;125(10):e55-e70. doi: 10.1161/CIRCRESAHA.119.315786. Epub 2019 Sep 24.
PMID; 31549940

Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth.
Nagdas S, Kashatus JA, Nascimento A, Hussain SS, Trainor RE, Pollock SR, Adair SJ, Michaels AD, Sesaki H, Stelow EB, Bauer TW, Kashatus DF.
Cell Rep. 2019 Aug 13;28(7):1845-1859.e5. doi: 10.1016/j.celrep.2019.07.031.
PMID: 31412251

A Coinfection Model to Evaluate Chlamydia Inc Protein Interactions.
Ende R, Derré I.
Methods Mol Biol. 2019;2042:205-218. doi: 10.1007/978-1-4939-9694-0_14.
PMID: 31385278

The sRNA DicF integrates oxygen sensing to enhance enterohemorrhagic Escherichia coli virulence via distinctive RNA control mechanisms.
Melson EM, Kendall MM.
Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14210-14215. doi: 10.1073/pnas.1902725116. Epub 2019 Jun 24.
PMID: 31235565

IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection.
Frisbee AL, Saleh MM, Young MK, Leslie JL, Simpson ME, Abhyankar MM, Cowardin CA, Ma JZ, Pramoonjago P, Turner SD, Liou AP, Buonomo EL, Petri WA Jr.
Nat Commun. 2019 Jun 20;10(1):2712. doi: 10.1038/s41467-019-10733-9.
PMID: 31221971

Chlamydia trachomatis and Chlamydia muridarum spectinomycin resistant vectors and a transcriptional fluorescent reporter to monitor conversion from replicative to infectious bacteria.
Cortina ME, Ende RJ, Bishop RC, Bayne C, Derré I.
PLoS One. 2019 Jun 6;14(6):e0217753. doi: 10.1371/journal.pone.0217753. eCollection 2019.
PMID: 31170215

Protocols to Interrogate the Interactions Between Neisseria gonorrhoeae and Primary Human Neutrophils.
Ragland SA, Criss AK.
Methods Mol Biol. 2019;1997:319-345. doi: 10.1007/978-1-4939-9496-0_19.
PMID: 31119632

Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection.
Saleh MM, Frisbee AL, Leslie JL, Buonomo EL, Cowardin CA, Ma JZ, Simpson ME, Scully KW, Abhyankar MM, Petri WA Jr.
Cell Host Microbe. 2019 May 8;25(5):756-765.e5. doi: 10.1016/j.chom.2019.03.003. Epub 2019 Apr 16.
PMID: 31003940

RalA and RalB relocalization to depolarized mitochondria depends on clathrin-mediated endocytosis and facilitates TBK1 activation.
Pollock SR, Schinlever AR, Rohani A, Kashatus JA, Kashatus DF.
PLoS One. 2019 Apr 17;14(4):e0214764. doi: 10.1371/journal.pone.0214764. eCollection 2019.
PMID: 30995277

Leveraging the effects of chloroquine on resistant malaria parasites for combination therapies.
Untaroiu AM, Carey MA, Guler JL, Papin JA.
BMC Bioinformatics. 2019 Apr 15;20(1):186. doi: 10.1186/s12859-019-2756-y.
PMID: 30987583

To B12 or not to B12: Five questions on the role of cobalamin in host-microbial interactions.
Rowley CA, Kendall MM.
PLoS Pathog. 2019 Jan 3;15(1):e1007479. doi: 10.1371/journal.ppat.1007479. eCollection 2019 Jan. Review. No abstract available.
PMID: 30605490

An integrated framework using high-dimensional mass cytometry and fluorescent flow cytometry identifies discrete B cell subsets in patients with red meat allergy.
Cox KM, Commins SP, Capaldo BJ, Workman LJ, Platts-Mills TAE, Amir ED, Lannigan JA, Schuyler AJ, Erickson LD.
Clin Exp Allergy. 2019 May;49(5):615-625. doi: 10.1111/cea.13322. Epub 2019 Jan 8.
PMID: 30506749