MIC Student Publications

Salmonella Typhimurium manipulates macrophage cholesterol homeostasis through the SseJ-mediated suppression of the host cholesterol transport protein ABCA1. Greene AR, Owen KA, Casanova JE. Cell Microbiol. 2021 Aug;23(8):e13329. doi: 10.1111/cmi.13329. Epub 2021 Apr 22. PMID: 33742761

Differential Expression of CD49a and CD49b Determines Localization and Function of Tumor-Infiltrating CD8⁺ T Cells.
Melssen MM, Lindsay RS, Stasiak K, Rodriguez AB, Briegel AM, Cyranowski S, Rutkowski MR, Conaway MR, Melief CJM, van der Burg SH, Eyo U, Slingluff CL Jr, Engelhard VH. Cancer Immunol Res. 2021 May;9(5):583-597. doi: 10.1158/2326-6066.CIR-20-0427. Epub 2021 Feb 22. PMID: 33619119; PMCID: PMC8102369.

Detergent wash improves vaccinated lymph node handling ex vivo.
Ball AG, Belanger MC, Pompano RR. J Immunol Methods. 2021 Feb;489:112943. doi: 10.1016/j.jim.2020.112943. Epub 2020 Dec 14. PMID: 33333059; PMCID: PMC7855487.

Characteristics of Immune Memory and Effector Activity to Cancer-Expressed MHC Class I Phosphopeptides Differ in Healthy Donors and Ovarian Cancer Patients.
Lulu AM, Cummings KL, Jeffery ED, Myers PT, Underwood D, Lacy RM, Chianese- Bullock KA, Slingluff CL Jr, Modesitt SC, Engelhard VH. Cancer Immunol Res. 2021 Aug 19. doi: 10.1158/2326-6066.CIR-21-0111. Epub ahead of print. PMID: 34413086.

IL-13 is a driver of COVID-19 severity.
Donlan AN, Sutherland TE, Marie C, Preissner S, Bradley BT, Carpenter RM, Sturek JM, Ma JZ, Moreau GB, Donowitz JR, Buck GA, Serrano MG, Burgess SL, Abhyankar MM, Mura C, Bourne PE, Preissner R, Young MK, Lyons GR, Loomba JJ, Ratcliffe SJ, Poulter MD, Mathers AJ, Day AJ, Mann BJ, Allen JE, Petri WA Jr. JCI Insight. 2021 Aug 9;6(15):e150107. doi: 10.1172/jci.insight.150107. PMID: 34185704; PMCID: PMC8410056.

Neuroimmune cleanup crews in brain injury.
Bolte AC, Lukens JR. Trends Immunol. 2021 Jun;42(6):480-494. doi: 10.1016/j.it.2021.04.003. Epub 2021 Apr 30. PMID: 33941486; PMCID: PMC8165004.

Mitochondrial dynamics in cancer stem cells.
Sessions DT, Kashatus DF. Cell Mol Life Sci. 2021 Apr;78(8):3803-3816. doi: 10.1007/s00018-021-03773-2. Epub 2021 Feb 13. PMID: 33580834.

De Novo Polycomb Recruitment: Lessons from Latent Herpesviruses.
Dochnal SA, Francois AK, Cliffe AR. Viruses. 2021 Jul 27;13(8):1470. doi: 10.3390/v13081470. PMID: 34452335; PMCID: PMC8402699.

Microbes exploit death-induced nutrient release by gut epithelial cells.
Anderson CJ, Medina CB, Barron BJ, Karvelyte L, Aaes TL, Lambertz I, Perry JSA, Mehrotra P, Gonçalves A, Lemeire K, Blancke G, Andries V, Ghazavi F, Martens A, van Loo G, Vereecke L, Vandenabeele P, Ravichandran KS. Nature. 2021 Aug;596(7871):262-267. doi: 10.1038/s41586-021-03785-9. Epub 2021 Aug 4. PMID: 34349263.

Licensing Natural Killers for Antiviral Immunity.
Cronk JM, Fafoutis E, Brown MG. Pathogens. 2021 Jul 19;10(7):908. doi: 10.3390/pathogens10070908. PMID: 34358058; PMCID: PMC8308748.

Putting the brakes on phagocytosis: “don’t-eat-me” signaling in physiology and disease.
Kelley SM, Ravichandran KS. EMBO Rep. 2021 Jun 4;22(6):e52564. doi: 10.15252/embr.202152564. Epub 2021 May 27. PMID: 34041845; PMCID: PMC8183410.

HLA class I and II associations with common enteric pathogens in the first year of life.
McCowin SE, Moreau GB, Haque R, Noble JA, McDevitt SL, Donowitz JR, Alam MM, Kirkpatrick BD, Petri WA, Marie C.  EBioMedicine. 2021 May;67:103346. doi: 10.1016/j.ebiom.2021.103346. Epub 2021 Apr 25. PMID: 33910121; PMCID: PMC8093888.

Lewis Blood-group Antigens Are Associated With Altered Susceptibility to Shigellosis.
Leslie JL, Weddle E, Yum LK, Lin Y, Jenior ML, Lee B, Ma JZ, Kirkpatrick BD, Nayak U, Platts-Mills JA, Agaisse HF, Haque R, Petri WA. Clin Infect Dis. 2021 Jun 1;72(11):e868-e871. doi: 10.1093/cid/ciaa1409. PMID: 32940644; PMCID: PMC8315233.

Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts.
Rodriguez AB, Peske JD, Woods AN, Leick KM, Mauldin IS, Meneveau MO, Young SJ, Lindsay RS, Melssen MM, Cyranowski S, Parriott G, Conaway MR, Fu YX, Slingluff CL Jr, Engelhard VH.  Cell Rep. 2021 Jul 20;36(3):109422. doi: 10.1016/j.celrep.2021.109422. PMID: 34289373; PMCID: PMC8362934.

Acute Lymph Node Slices Are a Functional Model System to Study Immunity Ex Vivo.
Belanger MC, Ball AG, Catterton MA, Kinman AWL, Anbaei P, Groff BD, Melchor SJ, Lukens JR, Ross AE, Pompano RR.  ACS Pharmacol Transl Sci. 2021 Jan 8;4(1):128-142. doi: 10.1021/acsptsci.0c00143. PMID: 33615167; PMCID: PMC7887751.

RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal.
Hussain SS, Tran TM, Ware TB, Luse MA, Prevost CT, Ferguson AN, Kashatus JA, Hsu KL, Kashatus DF. Cell Rep. 2021 Jul 27;36(4):109451. doi: 10.1016/j.celrep.2021.109451. PMID: 34320341; PMCID: PMC8344381.

Parasite protein pirates host cytoskeletal modulator during invasion.
McCowin S, Marie C, Petri WA Jr.  Trends Parasitol. 2021 Nov;37(11):937-939. doi: 10.1016/j.pt.2021.09.004. Epub 2021 Sep 28. PMID: 34598896.

A pathogen-specific sRNA influences enterohemorrhagic Escherichia coli fitness and virulence in part by direct interaction with the transcript encoding the ethanolamine utilization regulatory factor EutR.
Sauder AB, Kendall MM.  Nucleic Acids Res. 2021 Sep 30:gkab863. doi: 10.1093/nar/gkab863. Epub ahead of print. PMID: 34591974.

PML-NB-dependent type I interferon memory results in a restricted form of HSV latency.
Suzich JB, Cuddy SR, Baidas H, Dochnal S, Ke E, Schinlever AR, Babnis A, Boutell C, Cliffe AR.  EMBO Rep. 2021 Sep 6;22(9):e52547. doi: 10.15252/embr.202152547. Epub 2021 Jul 1. PMID: 34197022; PMCID: PMC8419685.

Rapid Fabrication by Digital Light Processing 3D Printing of a SlipChip with Movable Ports for Local Delivery to Ex Vivo Organ Cultures.
Catterton MA, Ball AG, Pompano RR.  Micromachines (Basel). 2021 Aug 20;12(8):993. doi: 10.3390/mi12080993. PMID: 34442615; PMCID: PMC8399530.

Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation.
Medina CB, Chiu YH, Stremska ME, Lucas CD, Poon I, Tung KS, Elliott MR, Desai B, Lorenz UM, Bayliss DA, Ravichandran KS. Immunity. 2021 Aug 10;54(8):1715-1727.e7. doi: 10.1016/j.immuni.2021.06.014. Epub 2021 Jul 21. PMID: 34283971; PMCID: PMC8363584.

Metabolites released from apoptotic cells act as tissue messengers.
Medina CB, Mehrotra P, Arandjelovic S, Perry JSA, Guo Y, Morioka S, Barron B, Walk SF, Ghesquière B, Krupnick AS, Lorenz U, Ravichandran KS.  Nature. 2020 Apr;580(7801):130-135. doi: 10.1038/s41586-020-2121-3. Epub 2020 Mar 18. PMID: 32238926; PMCID: PMC7217709.

Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis.
Bolte AC, Dutta AB, Hurt ME, Smirnov I, Kovacs MA, McKee CA, Ennerfelt HE, Shapiro D, Nguyen BH, Frost EL, Lammert CR, Kipnis J, Lukens JR.  Nat Commun. 2020 Sep 10;11(1):4524. doi: 10.1038/s41467-020-18113-4. PMID: 32913280; PMCID: PMC7483525.

Insights into Tumor-Associated Tertiary Lymphoid Structures: Novel Targets for Antitumor Immunity and Cancer Immunotherapy.
Rodriguez AB, Engelhard VH. Cancer Immunol Res. 2020 Nov;8(11):1338-1345. doi: 10.1158/2326-6066.CIR-20-0432. PMID: 33139300; PMCID: PMC7643396.

Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection.
Moreau GB, Burgess SL, Sturek JM, Donlan AN, Petri WA, Mann BJ. Am J Trop Med Hyg. 2020 Sep;103(3):1215-1219. doi: 10.4269/ajtmh.20-0762. PMID: 32723427; PMCID: PMC7470527.

Effect of Lipidation on the Localization and Activity of a Lysozyme Inhibitor in Neisseria gonorrhoeae.
Ragland SA, Gray MC, Melson EM, Kendall MM, Criss AK. J Bacteriol. 2020 Mar 26;202(8):e00633-19. doi: 10.1128/JB.00633-19. PMID: 32041800; PMCID: PMC7099142.

Mito Hacker: a set of tools to enable high-throughput analysis of mitochondrial network morphology.
Rohani A, Kashatus JA, Sessions DT, Sharmin S, Kashatus DF. Sci Rep. 2020 Nov 3;10(1):18941. doi: 10.1038/s41598-020-75899-5. PMID: 33144635; PMCID: PMC7642274.

Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production.
Upadhye A, Marshall M, Garmey JC, Bender TP, McNamara C. J Vis Exp. 2020 May 31;(159):10.3791/61003. doi: 10.3791/61003. PMID: 32538902; PMCID: PMC7863627.

Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling.
Mendu SK, Stremska ME, Schappe MS, Moser EK, Krupa JK, Rogers JS, Stipes EJ, Parker CA, Braciale TJ, Perry JSA, Desai BN. Sci Signal. 2020 Dec 8;13(661):eabb0619. doi: 10.1126/scisignal.abb0619. PMID: 33293462; PMCID: PMC7884026.

Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1.
Cuddy SR, Schinlever AR, Dochnal S, Seegren PV, Suzich J, Kundu P, Downs TK, Farah M, Desai BN, Boutell C, Cliffe AR. Elife. 2020 Dec 22;9:e58037. doi: 10.7554/eLife.58037. PMID: 33350386; PMCID: PMC7773336.

Imaging Flow Cytometry Analysis of CEACAM Binding to Opa-Expressing Neisseria
gonorrhoeae.
Werner LM, Palmer A, Smirnov A, Belcher Dufrisne M, Columbus L, Criss AK. Cytometry A. 2020 Jun 2. doi: 10.1002/cyto.a.24037. Epub ahead of print. PMID: 32484607.

Murine Endometrial Organoids to Model Chlamydia Infection.
Bishop RC, Boretto M, Rutkowski MR, Vankelecom H, Derré I. Front Cell Infect Microbiol. 2020 Aug 14;10:416. doi: 10.3389/fcimb.2020.00416. PMID: 32923409; PMCID: PMC7456808.

Host and Bacterial Glycolysis During Chlamydia trachomatis Infection.
Ende RJ, Derré I. Infect Immun. 2020 Sep 8:IAI.00545-20. doi: 10.1128/IAI.00545-20. Epub ahead of print. PMID: 32900818.

Models and molecular mechanisms of blood vessel co-option by cancer cells.
Zhang Y, Wang S, Dudley AC. Angiogenesis. 2020;23(1):17-25. doi:10.1007/s10456-019-09684 PMID: 31628560 PMCID: PMC7018564

The molecular biology and immune control of chronic Toxoplasma gondii infection.
Zhao XY, Ewald SE. J Clin Invest. 2020 Jul 1;130(7):3370-3380. doi:10.1172/JCI136226. PMID: 32609097; PMCID: PMC7324197.

The Ethanolamine-Sensing Transcription Factor EutR Promotes Virulence and Transmission during Citrobacter rodentium Intestinal Infection. Infect Immun.
Rowley CA, Sauder AB, Kendall MM. 2020 Aug 19;88(9):e00137-20. doi:10.1128/IAI.00137-20. PMID: 32631916; PMCID: PMC7440760.

RIPK3-dependent recruitment of low-inflammatory myeloid cells does not protect from systemic Salmonella infection.
Satkovich J, Anderson CJ, Medina Chris, Ottolini Matteo, Lukens J, Kendall MM*. mBio. 2020.

Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth.
Yao M, Ventura PB, Jiang Y, Rodriguez FJ, Wang L, Perry JSA, Yang Y, Wahl K, Crittenden RB, Bennett ML, Qi L, Gong CC, Li XN, Barres BA, Bender TP, Ravichandran KS, Janes KA, Eberhart CG, Zong H. Cell. 2020 Feb 6;180(3):502-520.e19. doi:10.1016/j.cell.2019.12.024. Epub 2020 Jan 23. PMID: 31983537; PMCID: PMC7259679.

Mosaic Analysis with Double Markers reveals IGF1R function in granule cell progenitors during cerebellar development.
Terry TT, Cheng T, Mahjoub M, Zong H. Dev Biol. 2020 Sep 15;465(2):130-143. doi: 10.1016/j.ydbio.2020.07.008. Epub 2020 Jul 19. PubMed PMID: 32697974; NIHMSID:NIHMS1616035.

Whole Genome Sequencing of Spontaneously Occurring Rat Natural Killer Large Granular Lymphocyte Leukemia Identifies JAK1 Somatic Activating Mutation.
Wang TT, Yang J, Dighe S, Schmachtenberg MW, Leigh NT, Farber E, Onengut-Gumuscu S, Feith DJ, Ratan A, Loughran TP Jr, Olson TL. Cancers (Basel).2020 Jan 3;12(1):126. doi: 10.3390/cancers12010126. PMID: 31947841; PMCID: PMC7017127.

Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection.
Moreau GB, Burgess SL, Sturek JM, Donlan AN, Petri WA, Mann BJ. Am J Trop Med Hyg. 2020 Sep;103(3):1215-1219. doi: 10.4269/ajtmh.20-0762. PMID: 32723427; PMCID: PMC7470527.

Dual Function of Aar, a Member of the New AraC Negative Regulator Family, in Escherichia coli Gene Expression.
Mickey AS, Nataro JP. Infect Immun. 2020 May 20;88(6):e00100-20. doi: 10.1128/IAI.00100-20. PMID: 32253248; PMCID: PMC7240098.

Type 2 Cytokines IL-4 and IL-5 Reduce Severe Outcomes from Clostridiodes difficile Infection.
Donlan A, Simpson ME, Petri WA Jr., M.D., Ph.D. Anaerobe 2020, in press.

IL-13 Predicts the Need for Mechanical Ventilation in COVID-19 Patients.
Donlan AD, Young M, Petri WA Jr., Abhyankar M. medRxiv 2020.06.18.20134353; doi:https://doi.org/10.1101/2020.06.18.20134353

Ten simple rules for reading a scientific paper.
Carey MA, Steiner KL, Petri WA Jr. PLoS Comput Biol. 2020 Jul 30;16(7):e1008032. doi: 10.1371/journal.pcbi.1008032. PMID: 32730251; PMCID: PMC7392212.

Considering the Immune System during Fecal Microbiota Transplantation for Clostridioides difficile Infection.
Frisbee AL, Petri WA Jr. Trends Mol Med. 2020 May;26(5):496-507. doi: 10.1016/j.molmed.2020.01.009. Epub 2020 Feb 17. PMID: 32359480; PMCID: PMC7198612.

Mucosal immunity and the eradication of polio.
Donlan AN, Petri WA Jr. Science. 2020 Apr 24;368(6489):362-363. doi: 10.1126/science.abb8588. PMID: 32327582.

The Inflammasome and Type-2 Immunity in Clostridium difficile Infection.
Donlan A, Petri WA Jr. Clin Colon Rectal Surg. 2020 Mar;33(2):67-72. doi: 10.1055/s-0040-1701231. Epub 2020 Feb 25. PMID: 32104158; PMCID: PMC7042014.

Inhibition of Amebic Cysteine Proteases Blocks Amebic Trogocytosis but Not Phagocytosis.
Gilmartin AA, Ralston KS, Petri WA. J Infect Dis. 2020 Apr 27;221(10):1734-1739. doi: 10.1093/infdis/jiz671. PMID: 31999350; PMCID: PMC7184912.

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection.
Batista SJ, Still KM, Johanson D, Thompson JA, OʼBrien CA, Lukens JR, Harris TH. Nat Commun. 2020 Jul 23;11(1):3687. doi: 10.1038/s41467-020-17491-z. PMID: 32703941; PMCID: PMC7378823.

Long-‘Trm’ protection of the CNS.
Kovacs MA, Harris TH. Nat Immunol. 2020 Aug;21(8):825-826. doi: 10.1038/s41590-020-0716-3. PMID: 32572243.

ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain.
O’Brien CA, Harris TH. PLoS One. 2020 Jan 24;15(1):e0228251. doi: 10.1371/journal.pone.0228251. PMID: 31978191; PMCID: PMC6980566.

Human T_H1 and T_H2 cells targeting rhinovirus and allergen coordinately promote allergic asthma.
Muehling LM, Heymann PW, Wright PW, Eccles JD, Agrawal R, Carper HT, Murphy DD, Workman LJ, Word CR, Ratcliffe SJ, Capaldo BJ, Platts-Mills TAE, Turner RB, Kwok WW, Woodfolk JA. J Allergy Clin Immunol. 2020 Sep;146(3):555-570. doi: 10.1016/j.jaci.2020.03.037. PMID: 32320734; PMCID: PMC7483727.

T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection.
Eccles JD, Turner RB, Kirk NA, Muehling LM, Borish L, Steinke JW, Payne SC, Wright PW, Thacker D, Lahtinen SJ, Lehtinen MJ, Heymann PW, Woodfolk JA. Cell Rep. 2020 Jan 14;30(2):351-366.e7. PMID: 31940481; PMCID: PMC6994188.

HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA.
Gray LR, Jackson RE, Jackson PEH, Bekiranov S, Rekosh D, Hammarskjöld ML.Retrovirology. 2019 Dec 16;16(1):40. doi: 10.1186/s12977-019-0505-y. PMID: 31842941; PMCID: PMC6916052

Ly49R activation receptor drives self-MHC-educated NK cell immunity against cytomegalovirus infection.
Gamache A, Cronk JM, Nash WT, Puchalski P, Gillespie A, Wei H, Gray L, Hammarskjold ML, Xu W, Brown MG. Proc Natl Acad Sci U S A. 2019 Dec 16;116(52):26768–78. doi: 10.1073/pnas.1913064117. Epub ahead of print. PMID: 31843910; PMCID: PMC6936569.

Natural selection for killer receptors and their MHC class I ligands: In pursuit of gene pairs that fit well in tandem.
Brown MG, Gamache A, Nash WT, Cronk J. J Leukoc Biol. 2019 Mar;105(3):489-495. doi: 10.1002/JLB.2RI0818-315R. Epub 2018 Nov 30. PMID: 30500089.

Type 3 Immunity during Clostridioides difficile Infection: Too Much of a Good Thing?
Saleh MM, Petri WA Jr. Infect Immun. 2019 Dec 17;88(1):e00306-19. doi: 10.1128/IAI.00306-19. PMID: 31570564; PMCID: PMC6921663.

IL-10 and ICOS Differentially Regulate T Cell Responses in the Brain during Chronic Toxoplasma gondii Infection.
O’Brien CA, Batista SJ, Still KM, Harris TH. J Immunol. 2019 Mar 15;202(6):1755-1766. doi: 10.4049/jimmunol.1801229. Epub 2019 Feb 4. PMID: 30718297; PMCID: PMC6401250

T cells in severe childhood asthma.
Paul AGA, Muehling LM, Eccles JD, Woodfolk JA. Clin Exp Allergy. 2019 May;49(5):564-581. doi: 10.1111/cea.13374. PMID: 30793397; PMCID: PMC6488378.

Models and molecular mechanisms of blood vessel co-option by cancer cells.
Zhang Y, Wang S, Dudley AC. Angiogenesis. 2019 Oct 18. doi: 10.1007/s10456-019-09684-y. [Epub ahead of print] Review. PMID: 31628560

Type 3 immunity during Clostridioides difficile infection: too much of a good thing?
Saleh MM, Petri WA Jr.
nfect Immun. 2019 Sep 30. pii: IAI.00306-19. doi: 10.1128/IAI.00306-19. [Epub ahead of print] Review.
PMID: 31570564

Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis.
Upadhye A, Srikakulapu P, Gonen A, Hendrikx S, Perry HM, Nguyen A, McSkimming C, Marshall MA, Garmey JC, Taylor AM, Bender TP, Tsimikas S, Holodick NE, Rothstein TL, Witztum JL, McNamara CA.
Circ Res. 2019 Oct 25;125(10):e55-e70. doi: 10.1161/CIRCRESAHA.119.315786. Epub 2019 Sep 24.
PMID; 31549940

Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth.
Nagdas S, Kashatus JA, Nascimento A, Hussain SS, Trainor RE, Pollock SR, Adair SJ, Michaels AD, Sesaki H, Stelow EB, Bauer TW, Kashatus DF.
Cell Rep. 2019 Aug 13;28(7):1845-1859.e5. doi: 10.1016/j.celrep.2019.07.031.
PMID: 31412251

A Coinfection Model to Evaluate Chlamydia Inc Protein Interactions.
Ende R, Derré I.
Methods Mol Biol. 2019;2042:205-218. doi: 10.1007/978-1-4939-9694-0_14.
PMID: 31385278

The sRNA DicF integrates oxygen sensing to enhance enterohemorrhagic Escherichia coli virulence via distinctive RNA control mechanisms.
Melson EM, Kendall MM.
Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14210-14215. doi: 10.1073/pnas.1902725116. Epub 2019 Jun 24.
PMID: 31235565

IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection.
Frisbee AL, Saleh MM, Young MK, Leslie JL, Simpson ME, Abhyankar MM, Cowardin CA, Ma JZ, Pramoonjago P, Turner SD, Liou AP, Buonomo EL, Petri WA Jr.
Nat Commun. 2019 Jun 20;10(1):2712. doi: 10.1038/s41467-019-10733-9.
PMID: 31221971

Chlamydia trachomatis and Chlamydia muridarum spectinomycin resistant vectors and a transcriptional fluorescent reporter to monitor conversion from replicative to infectious bacteria.
Cortina ME, Ende RJ, Bishop RC, Bayne C, Derré I.
PLoS One. 2019 Jun 6;14(6):e0217753. doi: 10.1371/journal.pone.0217753. eCollection 2019.
PMID: 31170215

Protocols to Interrogate the Interactions Between Neisseria gonorrhoeae and Primary Human Neutrophils.
Ragland SA, Criss AK.
Methods Mol Biol. 2019;1997:319-345. doi: 10.1007/978-1-4939-9496-0_19.
PMID: 31119632

Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection.
Saleh MM, Frisbee AL, Leslie JL, Buonomo EL, Cowardin CA, Ma JZ, Simpson ME, Scully KW, Abhyankar MM, Petri WA Jr.
Cell Host Microbe. 2019 May 8;25(5):756-765.e5. doi: 10.1016/j.chom.2019.03.003. Epub 2019 Apr 16.
PMID: 31003940

RalA and RalB relocalization to depolarized mitochondria depends on clathrin-mediated endocytosis and facilitates TBK1 activation.
Pollock SR, Schinlever AR, Rohani A, Kashatus JA, Kashatus DF.
PLoS One. 2019 Apr 17;14(4):e0214764. doi: 10.1371/journal.pone.0214764. eCollection 2019.
PMID: 30995277

Leveraging the effects of chloroquine on resistant malaria parasites for combination therapies.
Untaroiu AM, Carey MA, Guler JL, Papin JA.
BMC Bioinformatics. 2019 Apr 15;20(1):186. doi: 10.1186/s12859-019-2756-y.
PMID: 30987583

To B12 or not to B12: Five questions on the role of cobalamin in host-microbial interactions.
Rowley CA, Kendall MM.
PLoS Pathog. 2019 Jan 3;15(1):e1007479. doi: 10.1371/journal.ppat.1007479. eCollection 2019 Jan. Review. No abstract available.
PMID: 30605490

An integrated framework using high-dimensional mass cytometry and fluorescent flow cytometry identifies discrete B cell subsets in patients with red meat allergy.
Cox KM, Commins SP, Capaldo BJ, Workman LJ, Platts-Mills TAE, Amir ED, Lannigan JA, Schuyler AJ, Erickson LD.
Clin Exp Allergy. 2019 May;49(5):615-625. doi: 10.1111/cea.13322. Epub 2019 Jan 8.
PMID: 30506749

Principles of intracellular bacterial pathogen spread from cell to cell.
Weddle E, Agaisse H.
PLoS Pathog. 2018 Dec 13;14(12):e1007380. doi: 10.1371/journal.ppat.1007380. eCollection 2018 Dec. Review. No abstract available.
PMID: 30543716

The MtrCDE Efflux Pump Contributes to Survival of Neisseria gonorrhoeae From Human Neutrophils and Their Antimicrobial Components.
Handing JW, Ragland SA, Bharathan UV, Criss AK.
Front Microbiol. 2018 Nov 20;9:2688. doi: 10.3389/fmicb.2018.02688. eCollection 2018.
PMID: 30515136

MDVs: Spare the SOD and Spoil the Bug.
Hussain SS, Kashatus DF.
Cell Host Microbe. 2018 Nov 14;24(5):616-618. doi: 10.1016/j.chom.2018.10.013.
PMID: 30439336

Ethanolamine Influences Human Commensal Escherichia coli Growth, Gene Expression, and Competition with Enterohemorrhagic E. coli O157:H7.
Rowley CA, Anderson CJ, Kendall MM.
MBio. 2018 Oct 2;9(5). pii: e01429-18. doi: 10.1128/mBio.01429-18.
PMID: 30279284

The p53 Pathway in Glioblastoma.
Zhang Y, Dube C, Gibert M Jr, Cruickshanks N, Wang B, Coughlan M, Yang Y, Setiady I, Deveau C, Saoud K, Grello C, Oxford M, Yuan F, Abounader R.
Cancers (Basel). 2018 Sep 1;10(9). pii: E297. doi: 10.3390/cancers10090297. Review.
PMID: 30200436

Inferring Metabolic Mechanisms of Interaction within a Defined Gut Microbiota.
Medlock GL, Carey MA, McDuffie DG, Mundy MB, Giallourou N, Swann JR, Kolling GL, Papin JA.
Cell Syst. 2018 Sep 26;7(3):245-257.e7. doi: 10.1016/j.cels.2018.08.003. Epub 2018 Sep 5.
PMID: 30195437

Identification and Characterization of Tertiary Lymphoid Structures in Murine Melanoma.
Rodriguez AB, Peske JD, Engelhard VH.
Methods Mol Biol. 2018;1845:241-257. doi: 10.1007/978-1-4939-8709-2_14.
PMID: 30141017

Gonococcal Defenses against Antimicrobial Activities of Neutrophils.
Palmer A, Criss AK.
Trends Microbiol. 2018 Dec;26(12):1022-1034. doi: 10.1016/j.tim.2018.07.003. Epub 2018 Aug 13. Review.
PMID: 30115561

Making Contact: VAP Targeting by Intracellular Pathogens.
Stanhope R, Derré I.
Contact (Thousand Oaks). 2018 Jan-Dec;1. doi: 10.1177/2515256418775512. Epub 2018 May 17.
PMID: 30101212

Strength in diversity: Understanding the pathways to herpes simplex virus reactivation.
Suzich JB, Cliffe AR.
Virology. 2018 Sep;522:81-91. doi: 10.1016/j.virol.2018.07.011. Epub 2018 Jul 14. Review.
PMID: 30014861

Neisseria gonorrhoeae employs two protein inhibitors to evade killing by human lysozyme.
Ragland SA, Humbert MV, Christodoulides M, Criss AK.
PLoS Pathog. 2018 Jul 5;14(7):e1007080. doi: 10.1371/journal.ppat.1007080. eCollection 2018 Jul.
PMID: 29975775

After the Fact(or): Posttranscriptional Gene Regulation in Enterohemorrhagic Escherichia coli O157:H7.
Sauder AB, Kendall MM.
J Bacteriol. 2018 Sep 10;200(19). pii: e00228-18. doi: 10.1128/JB.00228-18. Print 2018 Oct 1. Review.
PMID: 29967119

Endocervical and Neutrophil Lipoxygenases Coordinate Neutrophil Transepithelial Migration to Neisseria gonorrhoeae.
Stevens JS, Gray MC, Morisseau C, Criss AK.
J Infect Dis. 2018 Oct 5;218(10):1663-1674. doi: 10.1093/infdis/jiy347.
PMID: 29905822

CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer.
Michaels AD, Newhook TE, Adair SJ, Morioka S, Goudreau BJ, Nagdas S, Mullen MG, Persily JB, Bullock T, Slingluff CL, Ravichandran KS, Parsons JT, Bauer TW.
Clin Cancer Res. 2017 Dec 29. pii: clincanres.2283.2017. doi: 10.1158/1078-0432.CCR-17-2283. [Epub ahead of print]
PMID: 29288236

Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy.
Wilson RJ, Drake JC, Cui D, Zhang M, Perry HM, Kashatus JA, Kusminski CM, Scherer PE, Kashatus DF, Okusa MD, Yan Z.
Mitochondrion. 2017 Dec 20. pii: S1567-7249(17)30196-4. doi: 10.1016/j.mito.2017.12.008. [Epub ahead of print]
PMID: 29274400

Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation.
Cho J, Lim SI, Yang BS, Hahn YS, Kwon I.
Sci Rep. 2017 Dec 21;7(1):18041. doi: 10.1038/s41598-017-18029-y.
PMID: 29269881

Regulation of Transcription Factors by Reactive Oxygen Species and Nitric Oxide in Vascular Physiology and Pathology.
Kohlgrüber S, Upadhye A, Dyballa-Rukes N, McNamara CA, Altschmied J.
Antioxid Redox Signal. 2017 May 1;26(13):679-699. doi: 10.1089/ars.2016.6946. Epub 2017 Jan 4. Review.
PMID: 27841660

Noncoding RNAs in Glioblastoma.
Zhang Y, Cruickshanks N, Pahuski M, Yuan F, Dutta A, Schiff D, Purow B, Abounader R.
In: De Vleeschouwer S, editor.
Glioblastoma [Internet]. Brisbane (AU): Codon Publications; 2017 Sep 27.
PMID: 29251875

Rev-RRE Functional Activity Differs Substantially Among Primary HIV-1 Isolates.
Jackson PE, Tebit DM, Rekosh D, Hammarskjold ML.
AIDS Res Hum Retroviruses. 2016 Sep;32(9):923-34. doi: 10.1089/AID.2016.0047. Epub 2016 Jun 3.
PMID: 27147495

Editorial: Masters of fate: the APC cytokine milieu as a key regulator of distinct Tfh cell subsets.
Cox KM, Erickson LD.
J Leukoc Biol. 2017 Jan;101(1):1-3. doi: 10.1189/jlb.1CE0816-351R. No abstract available.
PMID: 28049141

Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone.
Good ME, Chiu YH, Poon IK, Medina CB, Butcher JT, Mendu SK, DeLalio LJ, Lohman AW, Leitinger N, Barrett EJ, Lorenz UM, Desai BN, Jaffe IZ, Bayliss D, Isakson BE, Ravichandran KS.
Circ Res. 2017 Dec 13. pii: CIRCRESAHA.117.312380. doi: 10.1161/CIRCRESAHA.117.312380. [Epub ahead of print]
PMID: 29237722

Identification of actin beta-like 2 (ACTBL2) as novel, upregulated protein in colorectal cancer.
Ghazanfar S, Fatima I, Aslam M, Musharraf SG, Sherman NE, Moskaluk C, Fox JW, Akhtar MW, Sadaf S.
J Proteomics. 2017 Jan 30;152:33-40. doi: 10.1016/j.jprot.2016.10.011. Epub 2016 Oct 27.
PMID: 27989943

A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice.
Tang F, Zhang P, Ye P, Lazarski CA, Wu Q, Bergin IL, Bender TP, Hall MN, Cui Y, Zhang L, Jiang T, Liu Y, Zheng P.
Elife. 2017 Dec 5;6. pii: e32497. doi: 10.7554/eLife.32497. [Epub ahead of print]
PMID: 29206103

Basic Research in Bacterial Pathogenesis: “What’s Your Job about, Exactly?”
Derré I.
PLoS Pathog. 2016 Oct 13;12(10):e1005612. doi: 10.1371/journal.ppat.1005612. eCollection 2016 Oct. No abstract available.
PMID: 27736976 [PubMed – indexed for MEDLINE] Free PMC Article

Context-dependent compensation among phosphatidylserine-recognition receptors.
Penberthy KK, Rival C, Shankman LS, Raymond MH, Zhang J, Perry JSA, Lee CS, Han CZ, Onengut-Gumuscu S, Palczewski K, Lysiak JJ, Ravichandran KS.
Sci Rep. 2017 Nov 7;7(1):14623. doi: 10.1038/s41598-017-15191-1.
PMID: 29116131

Zinc acquisition mechanisms differ between environmental and virulent Francisella species.
Moreau GB, Qin A, Mann BJ.
J Bacteriol. 2017 Nov 6. pii: JB.00587-17. doi: 10.1128/JB.00587-17. [Epub ahead of print]
PMID: 29109188

Differential expression of homing receptor ligands on tumor associated vasculature that control CD8 effector T cell entry.
Woods AN, Wilson AL, Srivinisan N, Zeng J, Dutta AB, Peske JD, Tewalt EF, Gregg RK, Ferguson AR, Engelhard VH.
Cancer Immunol Res. 2017 Nov 2. pii: canimm.0190.2017. doi: 10.1158/2326-6066.CIR-17-0190. [Epub ahead of print]
PMID: 29097419

Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway.
Rucavado A, Nicolau CA, Escalante T, Kim J, Herrera C, Gutiérrez JM, Fox JW.
Toxins (Basel). 2016 Nov 24;8(12). pii: E349.
PMID: 27886127

Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI.
Perry HM, Huang L, Wilson RJ, Bajwa A, Sesaki H, Yan Z, Rosin DL, Kashatus DF, Okusa MD.
J Am Soc Nephrol. 2017 Oct 30. pii: ASN.2017060659. doi: 10.1681/ASN.2017060659. [Epub ahead of print]
PMID: 29084809

IncV, a FFAT motif-containing Chlamydia protein, tethers the endoplasmic reticulum to the pathogen-containing vacuole.
Stanhope R, Flora E, Bayne C, Derré I.
Proc Natl Acad Sci U S A. 2017 Oct 23. pii: 201709060. doi: 10.1073/pnas.1709060114. [Epub ahead of print]
PMID: 29078338

Salmonella enterica Serovar Typhimurium Strategies for Host Adaptation.
Anderson CJ, Kendall MM.
Front Microbiol. 2017 Oct 12;8:1983. doi: 10.3389/fmicb.2017.01983. eCollection 2017. Review.
PMID: 29075247

Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.
Olmez I, Love S, Xiao A, Manigat L, Randolph P, McKenna BD, Neal BP, Boroda S, Li M, Brenneman B, Abounader R, Floyd D, Lee J, Nakano I, Godlewski J, Bronisz A, Sulman EP, Mayo M, Gioeli D, Weber M, Harris TE, Purow B.
Neuro Oncol. 2017 Jun 29. doi: 10.1093/neuonc/nox119.

Microenvironmental agonists generate <i>de novo</i> phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL.
Jayappa KD, Portell CA, Gordon VL, Capaldo BJ, Bekiranov S, Axelrod MJ, Brett LK, Wulfkuhle JD, Gallagher RI, Petricoin EF, Bender TP, Williams ME, Weber MJ.
Blood Adv. 2017 Jun 13;1(14):933-946.
PMID: 29034364 [PubMed]

Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract: neutrophilic host response, sustained infection, and clinical sequelae.
Stevens JS, Criss AK.
Curr Opin Hematol. 2017 Oct 7. doi: 10.1097/MOH.0000000000000394. [Epub ahead of print]
PMID: 29016383

The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state.
Llewellyn RA, Thomas KS, Gutknecht MF, Bouton AH.
J Leukoc Biol. 2017 Oct;102(4):1069-1080. doi: 10.1189/jlb.1A0217-063R. Epub 2017 Jul 28.
PMID: 28754799

Culture conditions defining glioblastoma cells behavior: what is the impact for novel discoveries?
Ledur PF, Onzi GR, Zong H, Lenz G.
Oncotarget. 2017 Aug 11;8(40):69185-69197. doi: 10.18632/oncotarget.20193. eCollection 2017 Sep 15. Review.
PMID: 28978189

Neisseria: recent advances and future challenges.
Criss A, Tang C.
Pathog Dis. 2017 Nov 30;75(8). doi: 10.1093/femspd/ftx090. No abstract available.
PMID: 28957453

The Use of the Woodchuck as an Animal Model for Evaluation of Transarterial Embolization.
Wilkins LR, Stone JR, Mata J, Hawrylack A, Kubicka E, Brautigan DL.
J Vasc Interv Radiol. 2017 Oct;28(10):1467-1471. doi: 10.1016/j.jvir.2017.04.005.
PMID: 28941521

Th1 Signatures Are Present in the Lower Airways of Children with Severe Asthma, Regardless of Allergic Status.
Wisniewski JA, Muehling LM, Eccles JD, Capaldo BJ, Agrawal R, Shirley DA, Patrie JT, Workman LJ, Schuyler AJ, Lawrence MG, Teague WG, Woodfolk JA.
J Allergy Clin Immunol. 2017 Sep 19. pii: S0091-6749(17)31463-X. doi: 10.1016/j.jaci.2017.08.020. [Epub ahead of print]
PMID: 28939412

From bacterial killing to immune modulation: Recent insights into the functions of lysozyme.
Ragland SA, Criss AK.
PLoS Pathog. 2017 Sep 21;13(9):e1006512. doi: 10.1371/journal.ppat.1006512. eCollection 2017 Sep. Review.
PMID: 28934357

Characterization and in vitro activity of a branched peptide boronic acid that interacts with HIV-1 RRE RNA.
Wynn JE, Zhang W, Tebit DM, Gray LR, Hammarskjold ML, Rekosh D, Santos WL.
Bioorg Med Chem. 2016 Sep 1;24(17):3947-3952. doi: 10.1016/j.bmc.2016.04.009. Epub 2016 Apr 5.
PMID: 27091070

Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Dolina JS, Cechova S, Rudy CK, Sung SJ, Tang WW, Lee J, Hahn YS, Le TH.
J Immunol. 2017 Mar 15;198(6):2341-2351. doi: 10.4049/jimmunol.1502234. Epub 2017 Feb 3.
PMID: 28159899

The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Mohammed F, Stones DH, Zarling AL, Willcox CR, Shabanowitz J, Cummings KL, Hunt DF, Cobbold M, Engelhard VH, Willcox BE.
Oncotarget. 2017 Apr 8;8(33):54160-54172. doi: 10.18632/oncotarget.16952. eCollection 2017 Aug 15.
PMID: 28903331

SUMO and Chromatin Remodeling.
Wotton D, Pemberton LF, Merrill-Schools J.
Adv Exp Med Biol. 2017;963:35-50. doi: 10.1007/978-3-319-50044-7_3. Review.
PMID: 28197905

An NXF1 mRNA with a retained intron is expressed in hippocampal and neocortical neurons and is translated into a protein that functions as an Nxf1 cofactor.
Li Y, Bor YC, Fitzgerald MP, Lee KS, Rekosh D, Hammarskjold ML.
Mol Biol Cell. 2016 Dec 1;27(24):3903-3912. Epub 2016 Oct 5.
PMID: 27708137

Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.
Bukrejewska M, Derewenda U, Radwanska M, Engel DA, Derewenda ZS.
Acta Crystallogr D Struct Biol. 2017 Sep 1;73(Pt 9):767-774. doi: 10.1107/S2059798317010737. Epub 2017 Aug 15.
PMID: 28876240

Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells.
Krueger PD, Narayanan S, Surette FA, Brown MG, Sung SJ, Hahn YS.
J Leukoc Biol. 2017 Jan;101(1):329-338. doi: 10.1189/jlb.3A0516-225R. Epub 2016 Aug 4.
PMID: 27493244

Cardiolipin Synthesis and Outer Membrane Localization Are Required for Shigella flexneri Virulence.
Rossi RM, Yum L, Agaisse H, Payne SM.
MBio. 2017 Aug 29;8(4). pii: e01199-17. doi: 10.1128/mBio.01199-17.
PMID: 28851846

Inhibition of Amebic Lysosomal Acidification Blocks Amebic Trogocytosis and Cell Killing.
Gilmartin AA, Ralston KS, Petri WA Jr.
MBio. 2017 Aug 29;8(4). pii: e01187-17. doi: 10.1128/mBio.01187-17.
PMID: 28851845

Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells.
Penberthy KK, Buckley MW, Arandjelovic S, Ravichandran K.
PLoS One. 2017 Mar 7;12(3):e0173386. doi: 10.1371/journal.pone.0173386. eCollection 2017.
PMID: 28267764

‘This way please’: Apoptotic cells regulate phagocyte migration before and after engulfment.
Ariel A, Ravichandran KS.
Eur J Immunol. 2016 Jul;46(7):1583-6. doi: 10.1002/eji.201646505. Epub 2016 Jun 27.
PMID: 27345468

Combined CDK4/6 and mTOR inhibition is synergistic against glioblastoma via multiple mechanisms.
Olmez I, Brenneman B, Xiao A, Serbulea V, Benamar M, Zhang Y, Manigat L, Abbas T, Lee J, Nakano I, Godlewski J, Bronisz A, Abounader R, Leitinger N, Purow B.
Clin Cancer Res. 2017 Aug 16. pii: clincanres.0803.2017. doi: 10.1158/1078-0432.CCR-17-0803. [Epub ahead of print]
PMID: 28814434

Hijacking of Membrane Contact Sites by Intracellular Bacterial Pathogens.
Derré I.
Adv Exp Med Biol. 2017;997:211-223. doi: 10.1007/978-981-10-4567-7_16.
PMID: 28815533

Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice.
Sung SJ, Ge Y, Dai C, Wang H, Fu SM, Sharma R, Hahn YS, Yu J, Le TH, Okusa MD, Bolton WK, Lawler JR.
J Immunol. 2017 Apr 1;198(7):2589-2601. doi: 10.4049/jimmunol.1601565. Epub 2017 Feb 20.
PMID: 28219886

The AraC Negative Regulator family modulates the activity of histone-like proteins in pathogenic bacteria.
Santiago AE, Yan MB, Hazen TH, Sauder B, Meza-Segura M, Rasko DA, Kendall MM, Ruiz-Perez F, Nataro JP.
PLoS Pathog. 2017 Aug 14;13(8):e1006545. doi: 10.1371/journal.ppat.1006545. [Epub ahead of print]
PMID: 28806780

Two lytic transglycosylases in Neisseria gonorrhoeae impart resistance to killing by lysozyme and human neutrophils.
Ragland SA, Schaub RE, Hackett KT, Dillard JP, Criss AK.
Cell Microbiol. 2017 Mar;19(3). doi: 10.1111/cmi.12662. Epub 2016 Nov 3.
PMID: 27597434

Expression of scavenger receptor-AI promotes alternative activation of murine macrophages to limit hepatic inflammation and fibrosis.
Labonte AC, Sung SJ, Jennelle LT, Dandekar AP, Hahn YS.
Hepatology. 2017 Jan;65(1):32-43. doi: 10.1002/hep.28873. Epub 2016 Nov 22.
PMID: 27770558

Vaccines targeting helper T cells for cancer immunotherapy.
Melssen M, Slingluff CL Jr.
Curr Opin Immunol. 2017 Jul 26;47:85-92. doi: 10.1016/j.coi.2017.07.004. [Epub ahead of print] Review.
PMID: 28755541

The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state.
Llewellyn RA, Thomas KS, Gutknecht MF, Bouton AH.
J Leukoc Biol. 2017 Jul 28. pii: jlb.1A0217-063R. doi: 10.1189/jlb.1A0217-063R. [Epub ahead of print]
PMID: 28754799

High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa.
Etta EM, Mavhandu L, Manhaeve C, McGonigle K, Jackson P, Rekosh D, Hammarskjold ML, Bessong PO, Tebit DM.
AIDS Res Ther. 2017 Jul 27;14(1):36. doi: 10.1186/s12981-017-0161-z.
PMID: 28750647

Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during HCV infection.
Cobb DA, Golden-Mason L, Rosen HR, Hahn YS.
Hepatology. 2017 Jul 27. doi: 10.1002/hep.29409. [Epub ahead of print]
PMID: 28749570

Distinct Roles for Intracellular and Extracellular Lipids in Hepatitis C Virus Infection.
Narayanan S, Nieh AH, Kenwood BM, Davis CA, Tosello-Trampont AC, Elich TD, Breazeale SD, Ward E, Anderson RJ, Caldwell SH, Hoehn KL, Hahn YS.
PLoS One. 2016 Jun 9;11(6):e0156996. doi: 10.1371/journal.pone.0156996. eCollection 2016.
PMID: 27280294

Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes.
Shah M, Smolko CM, Kinicki S, Chapman ZD, Brautigan DL, Janes KA.
Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S244-S262. doi: 10.1074/mcp.O116.063487. Epub 2017 Feb 7.
PMID: 28174228

Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance.
Carey MA, Papin JA, Guler JL.
BMC Genomics. 2017 Jul 19;18(1):543. doi: 10.1186/s12864-017-3905-1.
PMID: 28724354

MEK2 is a prognostic marker and potential chemo-sensitizing target for glioma patients undergoing temozolomide treatment.
He H, Yao M, Zhang W, Tao B, Liu F, Li S, Dong Y, Zhang C, Meng Y, Li Y, Hu G, Luo C, Zong H, Lu Y.
Cell Mol Immunol. 2016 Sep;13(5):658-68. doi: 10.1038/cmi.2015.46. Epub 2015 Jul 20.
PMID: 26189368

CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis.
Margulieux KR, Fox JW, Nakamoto RK, Hughes MA.
MBio. 2016 May 10;7(3). pii: e00334-16. doi: 10.1128/mBio.00334-16.
PMID: 27165799

Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma.
Cruickshanks N, Zhang Y, Yuan F, Pahuski M, Gibert M, Abounader R.
Cancers (Basel). 2017 Jul 11;9(7). pii: E87. doi: 10.3390/cancers9070087. Review.
PMID: 28696366

The influence of the commensal microbiota on distal tumor-promoting inflammation.
Buchta Rosean CM, Rutkowski MR.
Semin Immunol. 2017 Jul 4. pii: S1044-5323(17)30019-2. doi: 10.1016/j.smim.2017.06.002. [Epub ahead of print] Review.
PMID: 28687194

The regulation of tumor cell physiology by mitochondrial dynamics.
Kashatus DF.
Biochem Biophys Res Commun. 2017 Jul 1. pii: S0006-291X(17)31323-2. doi: 10.1016/j.bbrc.2017.06.192. [Epub ahead of print]
PMID: 28676396

Detection and Quantification of Mitochondrial Fusion Using Imaging Flow Cytometry.
Nascimento A, Lannigan J, Kashatus D.
Curr Protoc Cytom. 2017 Jul 5;81:9.53.1-9.53.13. doi: 10.1002/cpcy.26.
PMID: 28678419

Functions of protein phosphatase-6 in NF-κB signaling and in lymphocytes.
Ziembik MA, Bender TP, Larner JM, Brautigan DL.
Biochem Soc Trans. 2017 Jun 15;45(3):693-701. doi: 10.1042/BST20160169. Review.
PMID: 28620030

A conserved leucine zipper motif in gammaherpesvirus ORF52 is critical for distinct microtubule rearrangements.
Loftus MS, Verville N, Kedes DH.
J Virol. 2017 Jun 14. pii: JVI.00304-17. doi: 10.1128/JVI.00304-17. [Epub ahead of print]
PMID: 28615210

SR proteins: To shuttle or not to shuttle, that is the question.
Hammarskjold ML, Rekosh D.
J Cell Biol. 2017 Jun 9. pii: jcb.201705009. doi: 10.1083/jcb.201705009. [Epub ahead of print]
PMID: 28600433

Adhesion GPCRs as Modulators of Immune Cell Function.
Hamann J, Hsiao CC, Lee CS, Ravichandran KS, Lin HH.
Handb Exp Pharmacol. 2016;234:329-350. Review.
PMID: 27832495

Symmetry breaking in spreading RAT2 fibroblasts requires the MAPK/ERK pathway scaffold RACK1 that integrates FAK, p190A-RhoGAP and ERK2 signaling.
Klímová Z, Bráborec V, Maninová M, Čáslavský J, Weber MJ, Vomastek T.
Biochim Biophys Acta. 2016 Sep;1863(9):2189-200. doi: 10.1016/j.bbamcr.2016.05.013. Epub 2016 May 19.
PMID: 27212270

Mesothelium expression of vascular cell adhesion molecule-1 (VCAM-1) is associated with an unfavorable prognosis in epithelial ovarian cancer (EOC).
Scalici JM, Arapovic S, Saks EJ, Atkins KA, Petroni G, Duska LR, Slack-Davis JK.
Cancer. 2017 May 15;123(6):977-984. doi: 10.1002/cncr.30415. Epub 2016 Nov 7.
PMID: 28263384

T Cells Deficient in the Tyrosine Phosphatase SHP-1 Resist Suppression by Regulatory T Cells.
Mercadante ER, Lorenz UM.
J Immunol. 2017 May 26. pii: 1602171. doi: 10.4049/jimmunol.1602171. [Epub ahead of print]
PMID: 28550200

Neisseria gonorrhoeae Evades Calprotectin-Mediated Nutritional Immunity and Survives Neutrophil Extracellular Traps by Production of TdfH.
Jean S, Juneau RA, Criss AK, Cornelissen CN.
Infect Immun. 2016 Sep 19;84(10):2982-94. doi: 10.1128/IAI.00319-16. Print 2016 Oct.
PMID: 27481245

Aurora Kinase A Promotes AR Degradation via the E3 Ligase CHIP.
Larner JM, Sarkar S, Brautigan DL.
Mol Cancer Res. 2017 May 23. pii: molcanres.0062.2017. doi: 10.1158/1541-7786.MCR-17-0062. [Epub ahead of print]
PMID: 28536143 [PubMed – as supplied by publisher]

IL233, A Novel IL-2 and IL-33 Hybrid Cytokine, Ameliorates Renal injury.
Stremska ME, Jose S, Sabapathy V, Huang L, Bajwa A, Kinsey GR, Sharma PR, Mohammad S, Rosin DL, Okusa MD, Sharma R.
J Am Soc Nephrol. 2017 May 24. pii: ASN.2016121272. doi: 10.1681/ASN.2016121272. [Epub ahead of print]
PMID: 28539382

Role of Serum Amyloid A, Granulocyte-Macrophage Colony-Stimulating Factor, and Bone Marrow Granulocyte-Monocyte Precursor Expansion in Segmented Filamentous Bacterium-Mediated Protection from Entamoeba histolytica.
Burgess SL, Saleh M, Cowardin CA, Buonomo E, Noor Z, Watanabe K, Abhyankar M, Lajoie S, Wills-Karp M, Petri WA Jr.
Infect Immun. 2016 Sep 19;84(10):2824-32. doi: 10.1128/IAI.00316-16. Print 2016 Oct.
PMID: 27456830

Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis.
Reon BJ, Anaya J, Zhang Y, Mandell J, Purow B, Abounader R, Dutta A.
PLoS Med. 2016 Dec 6;13(12):e1002192. doi: 10.1371/journal.pmed.1002192. eCollection 2016 Dec.
PMID: 27923049

Vancomycin Treatment Alters Humoral Immunity and Intestinal Microbiota in an Aged Mouse Model of Clostridium difficile Infection.
van Opstal E, Kolling GL, Moore JH 2nd, Coquery CM, Wade NS, Loo WM, Bolick DT, Shin JH, Erickson LD, Warren CA.
J Infect Dis. 2016 Jul 1;214(1):130-9. doi: 10.1093/infdis/jiw071. Epub 2016 Feb 24.
PMID: 26917573

The Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics.
Nagdas S, Kashatus DF.
Antioxidants (Basel). 2017 May 17;6(2). pii: E33. doi: 10.3390/antiox6020033. Review.
PMID: 28513539

Targetable T-type calcium channels drive glioblastoma.
Zhang Y, Cruickshanks N, Yuan F, Wang B, Pahuski M, Wulfkuhle J, Gallagher I, Koeppel AF, Hatef S, Papanicolas C, Lee J, Bar EE, Schiff D, Turner S, Petricoin EF, Gray LS, Abounader R.
Cancer Res. 2017 May 16. pii: canres.2347.2016. doi: 10.1158/0008-5472.CAN-16-2347. [Epub ahead of print]
PMID: 28512247

Lineage-Specific Metabolic Properties and Vulnerabilities of T Cells in the Demyelinating Central Nervous System.
Seki SM, Stevenson M, Rosen AM, Arandjelovic S, Gemta L, Bullock TNJ, Gaultier A.
J Immunol. 2017 May 15. pii: 1600825. doi: 10.4049/jimmunol.1600825. [Epub ahead of print]
PMID: 28507026

Restarting Lytic Gene Transcription at the Onset of Herpes Simplex Virus Reactivation.
Cliffe AR, Wilson AC.
J Virol. 2017 Jan 3;91(2). pii: e01419-16. doi: 10.1128/JVI.01419-16. Print 2017 Jan 15. Review.
PMID: 27807236

The Type Three Secretion System 2-Encoded Regulator EtrB Modulates Enterohemorrhagic Escherichia coli Virulence Gene Expression.
Luzader DH, Willsey GG, Wargo MJ, Kendall MM.
Infect Immun. 2016 Aug 19;84(9):2555-65. doi: 10.1128/IAI.00407-16. Print 2016 Sep.
PMID: 27324484

Bacillus anthracis Peptidoglycan Integrity Is Disrupted by the Chemokine CXCL10 through the FtsE/X Complex.
Margulieux KR, Liebov BK, Tirumala VSKKS, Singh A, Bushweller JH, Nakamoto RK, Hughes MA.
Front Microbiol. 2017 Apr 27;8:740. doi: 10.3389/fmicb.2017.00740. eCollection 2017.
PMID: 28496437

Neisserial Opa Protein-CEACAM Interactions: Competition for Receptors as a Means of Bacterial Invasion and Pathogenesis.
Martin JN, Ball LM, Solomon TL, Dewald AH, Criss AK, Columbus L.
Biochemistry. 2016 Aug 9;55(31):4286-94. doi: 10.1021/acs.biochem.6b00124. Epub 2016 Aug 1.
PMID: 27442026

Cinnamic Acid Derivatives Enhance the Efficacy of Transarterial Embolization in a Rat Model of Hepatocellular Carcinoma.
Wilkins LR, Brautigan DL, Wu H, Yarmohammadi H, Kubicka E, Serbulea V, Leitinger N, Liu W, Haaga JR.
Cardiovasc Intervent Radiol. 2017 Mar;40(3):430-437. doi: 10.1007/s00270-016-1515-y. Epub 2016 Nov 21.
PMID: 27872984 [PubMed – indexed for MEDLINE]

Extra! Extracellular Effector Delivery into Host Cells via the Type 3 Secretion System.
Kendall MM.
MBio. 2017 May 2;8(3). pii: e00594-17. doi: 10.1128/mBio.00594-17.
PMID: 28465427

Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.
Kim DW, Wu N, Kim YC, Cheng PF, Basom R, Kim D, Dunn CT, Lee AY, Kim K, Lee CS, Singh A, Gazdar AF, Harris CR, Eisenman RN, Park KS, MacPherson D.
Genes Dev. 2016 Jun 1;30(11):1289-99. doi: 10.1101/gad.279307.116.
PMID: 27298335

The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Mohammed F, Stones DH, Zarling AL, Willcox CR, Shabanowitz J, Cummings KL, Hunt DF, Cobbold M, Engelhard VH, Willcox BE.
Oncotarget. 2017 Apr 8. doi: 10.18632/oncotarget.16952.
PMID: 28446731

Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.
Kim DW, Wu N, Kim YC, Cheng PF, Basom R, Kim D, Dunn CT, Lee AY, Kim K, Lee CS, Singh A, Gazdar AF, Harris CR, Eisenman RN, Park KS, MacPherson D.
Genes Dev. 2016 Jun 1;30(11):1289-99. doi: 10.1101/gad.279307.116.
PMID: 27298335

Lysolecithin as feed additive enhances collagen expression and villus length in the jejunum of broiler chickens.
Brautigan DL, Li R, Kubicka E, Turner SD, Garcia JS, Weintraut ML, Wong EA.
Poult Sci. 2017 Apr 24. doi: 10.3382/ps/pex078.
PMID: 28444343

Pathogenic CD4⁺ T cells in patients with asthma.
Muehling LM, Lawrence MG, Woodfolk JA.
J Allergy Clin Immunol. 2017 Apr 22. pii: S0091-6749(17)30422-0. doi: 10.1016/j.jaci.2017.02.025. [Epub ahead of print] Review.
PMID: 28442213

CD11c-Expressing Cells Affect Regulatory T Cell Behavior in the Meninges during Central Nervous System Infection.
O’Brien CA, Overall C, Konradt C, O’Hara Hall AC, Hayes NW, Wagage S, John B, Christian DA, Hunter CA, Harris TH.
J Immunol. 2017 Apr 7. pii: 1601581. doi: 10.4049/jimmunol.1601581. [Epub ahead of print]
PMID: 28389591

Immunoregulatory Role of NK Cells in Tissue Inflammation and Regeneration.
Tosello-Trampont A, Surette FA, Ewald SE, Hahn YS.
Front Immunol. 2017 Mar 20;8:301. doi: 10.3389/fimmu.2017.00301. eCollection 2017. Review.
PMID: 28373874

High-Throughput Particle Uptake Analysis by Imaging Flow Cytometry.
Smirnov A, Solga MD, Lannigan J, Criss AK.
Curr Protoc Cytom. 2017 Apr 3;80:11.22.1-11.22.17. doi: 10.1002/cpcy.19.
PMID: 28369762

Oncogenic effects of evolutionarily conserved noncoding RNA ECONEXIN on gliomagenesis.
Deguchi S, Katsushima K, Hatanaka A, Shinjo K, Ohka F, Wakabayashi T, Zong H, Natsume A, Kondo Y.
Oncogene. 2017 Apr 3. doi: 10.1038/onc.2017.88.
PMID: 28368417

A Co-infection Model System and the Use of Chimeric Proteins to Study <i>Chlamydia</i> Inclusion Proteins Interaction.
Han Y, Derré I.
Front Cell Infect Microbiol. 2017 Mar 14;7:79. doi: 10.3389/fcimb.2017.00079. eCollection 2017 Mar 14.
PMID: 28352612

Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia.
Michels KR, Zhang Z, Bettina AM, Cagnina RE, Stefanova D, Burdick MD, Vaulont S, Nemeth E, Ganz T, Mehrad B.
JCI Insight. 2017 Mar 23;2(6):e92002. doi: 10.1172/jci.insight.92002.
PMID: 28352667

Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation.
Han CZ, Juncadella IJ, Kinchen JM, Buckley MW, Klibanov AL, Dryden K, Onengut-Gumuscu S, Erdbrügger U, Turner SD, Shim YM, Tung KS, Ravichandran KS.
Nature. 2016 Nov 24;539(7630):570-574. doi: 10.1038/nature20141. Epub 2016 Nov 7.
PMID: 27820945

Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis.
Noor Z, Watanabe K, Abhyankar MM, Burgess SL, Buonomo EL, Cowardin CA, Petri WA Jr.
MBio. 2017 Feb 28;8(1). pii: e02329-16. doi: 10.1128/mBio.02329-16.
PMID: 28246365

Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia.
Ramakrishnan G, Wright M, Alam M, Naylor C, Kabir M, Zerin A, Ferdous T, Pedersen K, Hennig BJ, Donowitz JR, Wegmuller R, Haque R, Petri WA Jr, Herbein J, Gilchrist CA.
Diagn Microbiol Infect Dis. 2017 Mar;87(3):272-274. doi: 10.1016/j.diagmicrobio.2016.11.011.
PMID: 27916543

Understanding the Snake Venom Metalloproteinases: An Interview with Jay Fox and José María Gutiérrez.
Fox JW, Gutiérrez JM.
Toxins (Basel). 2017 Jan 16;9(1). pii: E33. doi: 10.3390/toxins9010033.
PMID: 28275208

Lysophosphatidic acid counteracts glucagon-induced hepatocyte glucose production via STAT3.
Taddeo EP, Hargett SR, Lahiri S, Nelson ME, Liao JA, Li C, Slack-Davis JK, Tomsig JL, Lynch KR, Yan Z, Harris TE, Hoehn KL.
Sci Rep. 2017 Dec;7(1):127. doi: 10.1038/s41598-017-00210-y.
PMID: 28273928

Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells.
Penberthy KK, Buckley MW, Arandjelovic S, Ravichandran K.
PLoS One. 2017 Mar 7;12(3):e0173386. doi: 10.1371/journal.pone.0173386.
PMID: 28267764

Mesothelium expression of vascular cell adhesion molecule-1 (VCAM-1) is associated with an unfavorable prognosis in epithelial ovarian cancer (EOC).
Scalici JM, Arapovic S, Saks EJ, Atkins KA, Petroni G, Duska LR, Slack-Davis JK.
Cancer. 2017 May 15;123(6):977-984. doi: 10.1002/cncr.30415.
PMID: 28263384

Herpes Simplex Virus Latency: The DNA Repair-Centered Pathway.
Brown JC.
Adv Virol. 2017;2017:7028194. doi: 10.1155/2017/7028194. Review.
PMID: 28255301

The E3 Ligase CHIP Mediates p21 Degradation to Maintain Radioresistance.
Biswas K, Sarkar S, Du K, Brautigan DL, Abbas T, Larner JM.
Mol Cancer Res. 2017 Feb 23. pii: molcanres.0466.2016. doi: 10.1158/1541-7786.MCR-16-0466. [Epub ahead of print]
PMID: 28232384

SUMO and Chromatin Remodeling.
Wotton D, Pemberton LF, Merrill-Schools J.
Adv Exp Med Biol. 2017;963:35-50. doi: 10.1007/978-3-319-50044-7_3.
PMID: 28197905

Hematopoietic pannexin 1 function is critical for neuropathic pain.
Weaver JL, Arandjelovic S, Brown G, K Mendu S, S Schappe M, Buckley MW, Chiu YH, Shu S, Kim JK, Chung J, Krupa J, Jevtovic-Todorovic V, Desai BN, Ravichandran KS, Bayliss DA.
Sci Rep. 2017 Feb 14;7:42550. doi: 10.1038/srep42550.
PMID: 28195232

Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers.
Illendula A, Gilmour J, Grembecka J, Tirumala VS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, Mishra L, Adli M, Castilla LH, Rajewski RA, Janes KA, Guzman ML, Bonifer C, Bushweller JH.
EBioMedicine. 2016 Jun;8:117-31. doi: 10.1016/j.ebiom.2016.04.032.
PMID: 27428424

Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.
Benamar M, Guessous F, Du K, Corbett P, Obeid J, Gioeli D, Slingluff CL Jr, Abbas T.
EBioMedicine. 2016 Aug;10:85-100. doi: 10.1016/j.ebiom.2016.06.023.
PMID: 27333051

Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes.
Shah M, Smolko CM, Kinicki S, Chapman ZD, Brautigan DL, Janes KA.
Mol Cell Proteomics. 2017 Feb 7. pii: mcp.O116.063487. doi: 10.1074/mcp.O116.063487. [Epub ahead of print]
PMID: 28174228

Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Dolina JS, Cechova S, Rudy CK, Sung SJ, Tang WW, Lee J, Hahn YS, Le TH.
J Immunol. 2017 Feb 3. pii: 1502234. doi: 10.4049/jimmunol.1502234.
PMID: 28159899

Editorial: Masters of fate: the APC cytokine milieu as a key regulator of distinct Tfh cell subsets.
Cox KM, Erickson LD.
J Leukoc Biol. 2017 Jan;101(1):1-3. doi: 10.1189/jlb.1CE0816-351R. No abstract available.
PMID: 28049141

Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway.
Rucavado A, Nicolau CA, Escalante T, Kim J, Herrera C, Gutiérrez JM, Fox JW.
Toxins (Basel). 2016 Nov 24;8(12). pii: E349.
PMID: 27886127 [Unknown status]

Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis.
Rucavado A, Nicolau CA, Escalante T, Kim J, Herrera C, Gutiérrez JM, Fox JW.
Toxins (Basel). 2016 Nov 24;8(12). pii: E349.
PMID: 27886127

Identification of actin beta-like 2 (ACTBL2) as novel, upregulated protein in colorectal cancer.
Ghazanfar S, Fatima I, Aslam M, Musharraf SG, Sherman NE, Moskaluk C, Fox JW, Akhtar MW, Sadaf S.
J Proteomics. 2016 Oct 27;152:33-40. doi: 10.1016/j.jprot.2016.10.011.
PMID: 27989943

Cinnamic Acid Derivatives Enhance the Efficacy of Transarterial Embolization in a Rat Model of Hepatocellular Carcinoma.
Wilkins LR, Brautigan DL, Wu H, Yarmohammadi H, Kubicka E, Serbulea V, Leitinger N, Liu W, Haaga JR. Cardiovasc Intervent Radiol. 2016 Nov 21.
PMID: 27872984

Regulation of transcription factors by reactive oxygen species and nitric oxide in vascular physiology and pathology.
Kohlgrüber S, Upadhye A, Dyballa-Rukes N, McNamara CA, Altschmied J.
Antioxid Redox Signal. 2016 Nov 14.
PMID: 27841660

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas.
Roller DG, Capaldo B, Bekiranov S, Mackey AJ, Conaway MR, Petricoin EF, Gioeli D, Weber MJ.
Oncotarget. 2016 Jan 19;7(3):2734-53. doi: 10.18632/oncotarget.6548.
PMID: 26673621

Molecular and Cellular Mechanisms of Shigella flexneri Dissemination.
Agaisse H.
Front Cell Infect Microbiol. 2016 Mar 11;6:29. doi: 10.3389/fcimb.2016.00029. Review.
PMID: 27014639

Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation.
Han CZ, Juncadella IJ, Kinchen JM, Buckley MW, Klibanov AL, Dryden K, Onengut-Gumuscu S, Erdbrügger U, Turner SD, Shim YM, Tung KS, Ravichandran KS.
Nature. 2016 Nov 7. doi: 10.1038/nature20141.
PMID: 27820945

Restarting Lytic Gene Transcription at the Onset of Herpes Simplex Virus Reactivation.
Cliffe AR, Wilson AC.
J Virol. 2016 Nov 2. pii: JVI.01419-16. [Epub ahead of print]
PMID: 27807236

Environmental Enteropathy, Oral Vaccine Failure and Growth Faltering in Infants in Bangladesh
Naylor C, Lu M, Haque R, Mondal D, Buonomo E, Nayak U, Mychaleckyj JC, Kirkpatrick B, Colgate R, Carmolli M, Dickson D, van der Klis F, Weldon W, Steven Oberste M; PROVIDE study teams., Ma JZ, Petri WA Jr.
EBioMedicine. 2015 Sep 25;2(11):1759-66. doi: 10.1016/j.ebiom.2015.09.036.
PMID: 26870801

Acute Virus Control Mediated by Licensed NK Cells Sets Primary CD8+ T Cell Dependence on CD27 Costimulation.
Teoh JJ, Gamache AE, Gillespie AL, Stadnisky MD, Yagita H, Bullock TN, Brown MG.
J Immunol. 2016 Oct 24. pii: 1601049. [Epub ahead of print]
PMID: 27798162

A Comprehensive View of the Structural and Functional Alterations of Extracellular Matrix by Snake Venom Metalloproteinases (SVMPs): Novel Perspectives on the Pathophysiology of Envenoming.
Gutiérrez JM, Escalante T, Rucavado A, Herrera C, Fox JW.
Toxins (Basel). 2016 Oct 22;8(10). pii: E304. Review.
PMID: 27782073

The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria.
Billings EA, Lee CS, Owen KA, D’Souza RS, Ravichandran KS, Casanova JE.
Sci Signal. 2016 Feb 2;9(413):ra14. doi: 10.1126/scisignal.aac6250.
PMID: 26838550

Expression of scavenger receptor-AI promotes alternative activation of murine macrophages to limit hepatic inflammation and fibrosis.
Labonte AC, Sung SJ, Jennelle LT, Dandekar AP, Hahn YS.
Hepatology. 2016 Oct 22. doi: 10.1002/hep.28873.
PMID: 27770558 [PubMed]

Basic Research in Bacterial Pathogenesis: “What’s Your Job about, Exactly?
Derré I.
PLoS Pathog. 2016 Oct 13;12(10):e1005612. doi: 10.1371/journal.ppat.1005612. No abstract available.
PMID: 27736976

Neisseria gonorrhoeae Evades Calprotectin-Mediated Nutritional Immunity and Survives Neutrophil Extracellular Traps by Production of TdfH.
Jean S, Juneau RA, Criss AK, Cornelissen CN.
nfect Immun. 2016 Sep 19;84(10):2982-94. doi: 10.1128/IAI.00319-16. Print 2016 Oct.
PMID: 27481245

Neisserial Opa Protein-CEACAM Interactions: Competition for Receptors as a Means of Bacterial Invasion and Pathogenesis.
Martin JN, Ball LM, Solomon TL, Dewald AH, Criss AK, Columbus L.
Biochemistry. 2016 Aug 9;55(31):4286-94. doi: 10.1021/acs.biochem.6b00124. Epub 2016 Aug 1.
PMID: 27442026

DNA Zip Codes in Herpesvirus Genomes
Brown, J.C
(2016) Journal of Virology and Antiviral Research 5:2.

Two lytic transglycosylases in Neisseria gonorrhoeae impart resistance to killing by lysozyme and human neutrophils.
Ragland SA, Schaub RE, Hackett KT, Dillard JP, Criss AK.
Cell Microbiol. 2016 Sep 6. doi: 10.1111/cmi.12662. [Epub ahead of print]
PMID: 27597434

Circulating Memory CD4+ T Cells Target Conserved Epitopes of Rhinovirus Capsid Proteins and Respond Rapidly to Experimental Infection in Humans.
Muehling LM, Mai DT, Kwok WW, Heymann PW, Pomés A, Woodfolk JA.
J Immunol. 2016 Sep 2. pii: 1600663. [Epub ahead of print]
PMID: 27591323

The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia.
Cowardin CA, Buonomo EL, Saleh MM, Wilson MG, Burgess SL, Kuehne SA, Schwan C, Eichhoff AM, Koch-Nolte F, Lyras D, Aktories K, Minton NP, Petri WA Jr.
Nat Microbiol. 2016 Jul 11;1(8):16108. doi: 10.1038/nmicrobiol.2016.108.
PMID: 27573114

Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis.
Fond AM, Ravichandran KS.
Adv Exp Med Biol. 2016;930:25-49. doi: 10.1007/978-3-319-39406-0_2.
PMID: 27558816 [PubMed – in process]

Salmonella Manipulates Autophagy to “Serve and Protect”.
Owen KA, Casanova JE.
Cell Host Microbe. 2015 Nov 11;18(5):517-9. doi: 10.1016/j.chom.2015.10.020.
PMID: 26567504 [PubMed – indexed for MEDLINE]

Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells.
Krueger PD, Narayanan S, Surette FA, Brown MG, Sung SJ, Hahn YS.
J Leukoc Biol. 2016 Aug 4. pii: jlb.3A0516-225R. [Epub ahead of print]
PMID: 27493244 [PubMed – as supplied by publisher]

αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer Through JNK1-Mediated Activation of Androgen Receptor.
Lu H, Wang T, Li J, Fedele C, Liu Q, Zhang J, Jiang Z, Jain D, Iozzo RV, Violette SM, Weinreb PH, Davis RJ, Gioeli D, Fitzgerald TJ, Altieri DC, Languino LR.
Cancer Res. 2016 Jul 22. pii: canres.0543.2016. [Epub ahead of print]
PMID: 27450452 [PubMed – as supplied by publisher]

The Dynamics of Apoptotic Cell Clearance.
Elliott MR, Ravichandran KS.
Dev Cell. 2016 Jul 25;38(2):147-60. doi: 10.1016/j.devcel.2016.06.029. Review.
PMID: 27459067

Effect of intercalator and Lewis acid-base branched peptide complex formation: boosting affinity towards HIV-1 RRE RNA.
Wynn JE, Zhang W, Tebit DM, Gray LR, Hammarskjold ML, Rekosh D, Santos WL.
Medchemcomm. 2016 Jul 1;7(7):1436-1440. Epub 2016 Jun 6.
PMID: 27453773 [PubMed]

Role of Serum Amyloid A, GM-CSF and Bone Marrow Granulocyte-Monocyte Precursor Expansion in Segmented Filamentous Bacteria-mediated Protection from Entamoeba histolytica.
Burgess SL, Saleh M, Cowardin CA, Buonomo E, Noor Z, Watanabe K, Abhyankar M, Lajoie S, Wills-Karp M, Petri WA Jr.
Infect Immun. 2016 Jul 25. pii: IAI.00316-16. [Epub ahead of print]
PMID: 27456830

High-throughput detection and quantification of mitochondrial fusion through imaging flow cytometry.
Nascimento A, Lannigan J, Kashatus D.
Cytometry A. 2016 Jul 7. doi: 10.1002/cyto.a.22891. [Epub ahead of print]
PMID: 27387508

Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.
Denny SK, Yang D, Chuang CH, Brady JJ, Lim JS, Grüner BM, Chiou SH, Schep AN, Baral J, Hamard C, Antoine M, Wislez M, Kong CS, Connolly AJ, Park KS, Sage J, Greenleaf WJ, Winslow MM.
Cell. 2016 Jun 29. pii: S0092-8674(16)30655-9. doi: 10.1016/j.cell.2016.05.052.
PMID: 27374332

Lobular Breast Cancer and Abdominal Metastases: A Retrospective Review and Impact on Survival.
Winn JS, Baker MG, Fanous IS, Slack-Davis JK, Atkins KA, Dillon PM.
Oncology. 2016 Jun 30. [Epub ahead of print]
PMID: 27355204

The Immune Landscape in Nonalcoholic Steatohepatitis.
Narayanan S, Surette FA, Hahn YS.
Immune Netw. 2016 Jun;16(3):147-58. doi: 10.4110/in.2016.16.3.147. Epub 2016 Jun 17. Review.
PMID: 27340383 [PubMed]

Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-γ Production by Altering Cellular Metabolism via Arginase-1.
Goh CC, Roggerson KM, Lee HC, Golden-Mason L, Rosen HR, Hahn YS.
J Immunol. 2016 Mar 1;196(5):2283-92. doi: 10.4049/jimmunol.1501881. Epub 2016 Jan 29.
PMID: 26826241

Genomic Modifiers of Natural Killer Cells, Immune Responsiveness and Lymphoid Tissue Remodeling Together Increase Host Resistance to Viral Infection.
Gillespie AL, Teoh J, Lee H, Prince J, Stadnisky MD, Anderson M, Nash W, Rival C, Wei H, Gamache A, Farber CR, Tung K, Brown MG.
PLoS Pathog. 2016 Feb 4;12(2):e1005419. doi: 10.1371/journal.ppat.1005419. eCollection 2016 Feb.
PMID: 26845690

Microbiota-Regulated IL-25 Increases Eosinophil Number to Provide Protection during Clostridium difficile Infection.
Buonomo EL, Cowardin CA, Wilson MG, Saleh MM, Pramoonjago P, Petri WA Jr.
Cell Rep. 2016 Jun 22. pii: S2211-1247(16)30726-4. doi: 10.1016/j.celrep.2016.06.007. [Epub ahead of print]
PMID: 27346351

‘This way please’: Apoptotic cells regulate phagocyte migration before and after engulfment.
Ariel A, Ravichandran KS.
Eur J Immunol. 2016 Jun 27. doi: 10.1002/eji.201646505. [Epub ahead of print]
PMID: 27345468

Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.
Benamar M, Guessous F, Du K, Corbett P, Obeid J, Gioeli D, Slingluff CL Jr, Abbas T.
EBioMedicine. 2016 Jun 16. pii: S2352-3964(16)30279-1. doi: 10.1016/j.ebiom.2016.06.023. [Epub ahead of print]
PMID: 27333051

Rapid proteomic responses to a near-lethal heat stress in the salt marsh mussel Geukensia demissa.
Fields PA, Burmester EM, Cox KM, Karch KR.
J Exp Biol. 2016 Jun 22. pii: jeb.141176. [Epub ahead of print]
PMID: 27335449

The ETT2-encoded regulator EtrB modulates enterohemorrhagic Escherichia coli virulence gene expression.
Luzader DH, Willsey GG, Wargo MJ, Kendall MM.
Infect Immun. 2016 Jun 20. pii: IAI.00407-16. [Epub ahead of print]
PMID: 27324484

Ret and Etv4 Promote Directed Movements of Progenitor Cells during Renal Branching Morphogenesis.
Riccio P, Cebrian C, Zong H, Hippenmeyer S, Costantini F.
PLoS Biol. 2016 Feb 19;14(2):e1002382. doi: 10.1371/journal.pbio.1002382. eCollection 2016 Feb. Erratum in: PLoS Biol. 2016 Jun;14(6):e1002488.
PMID: 26894589

How Mouse Macrophages Sense What Is Going On.
Ley K, Pramod AB, Croft M, Ravichandran KS, Ting JP.Front Immunol. 2016 Jun 2;7:204. doi: 10.3389/fimmu.2016.00204. eCollection 2016. Review.
PMID: 27313577 [PubMed]

Distinct Roles for Intracellular and Extracellular Lipids in Hepatitis C Virus Infection.
Narayanan S, Nieh AH, Kenwood BM, Davis CA, Tosello-Trampont AC, Elich TD, Breazeale SD, Ward E, Anderson RJ, Caldwell SH, Hoehn KL, Hahn YS.
PLoS One. 2016 Jun 9;11(6):e0156996. doi: 10.1371/journal.pone.0156996. eCollection 2016.
PMID: 27280294

Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis.
Harakal J, Rival C, Qiao H, Tung KS.
J Immunol. 2016 Jun 3. pii: 1502344. [Epub ahead of print]
PMID: 27259856

Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.
Kim DW, Wu N, Kim YC, Cheng PF, Basom R, Kim D, Dunn CT, Lee AY, Kim K, Lee CS, Singh A, Gazdar AF, Harris CR, Eisenman RN, Park KS, MacPherson D.
Genes Dev. 2016 Jun 1;30(11):1289-99. doi: 10.1101/gad.279307.116. PMID:  27298335

Rev-RRE Functional Activity Differs Substantially Among Primary HIV-1 Isolates.
Jackson PE, Tebit DM, Rekosh D, Hammarskjold ML.
AIDS Res Hum Retroviruses. 2016 Jun 3. [Epub ahead of print]  PMID: 27147495

Do not let death do us part: ‘find-me’ signals in communication between dying cells and the phagocytes.
Medina CB, Ravichandran KS. Cell Death Differ. 2016 Jun;23(6):979-89. doi: 10.1038/cdd.2016.13. Epub 2016 Feb 19. Review. PMID: 26891690

The microbiota and immune response during Clostridium difficile infection.
Buonomo EL, Petri WA Jr.
Anaerobe. 2016 May 19. pii: S1075-9964(16)30062-2. doi: 10.1016/j.anaerobe.2016.05.009. [Epub ahead of print]
PMID: 27212111 [PubMed – as supplied by publisher]

Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression.
Mercadante ER, Lorenz UM. Front Immunol. 2016 May 18;7:193. doi: 10.3389/fimmu.2016.00193. eCollection 2016. Review. PMID: 27242798

M-CSF Mediates Host Defense during Bacterial Pneumonia by Promoting the Survival of Lung and Liver Mononuclear Phagocytes.
Bettina A, Zhang Z, Michels K, Cagnina RE, Vincent IS, Burdick MD, Kadl A, Mehrad B.
J Immunol. 2016 May 4. pii: 1600306. [Epub ahead of print]
PMID: 27183631 [PubMed – as supplied by publisher]

Microbiota and pathogen ‘pas de deux’: setting up and breaking down barriers to intestinal infection.
McKenney ES, Kendall MM. Pathog Dis. 2016 May 31. pii: ftw051. [Epub ahead of print] PMID: 27252177

The Metalloprotease Mpl Supports Listeria monocytogenes Dissemination through Resolution of Membrane Protrusions into Vacuoles.
Alvarez DE, Agaisse H. Infect Immun. 2016 May 24;84(6):1806-14. doi: 10.1128/IAI.00130-16. Print 2016 Jun. PMID: 27068088

Symmetry breaking in spreading RAT2 fibroblasts requires the MAPK/ERK pathway scaffold RACK1 that integrates FAK, p190A-RhoGAP and ERK2 signaling.
Klímová Z, Bráborec V, Maninová M, Čáslavský J, Weber MJ, Vomastek T. Biochim Biophys Acta. 2016 May 19;1863(9):2189-2200. doi: 10.1016/j.bbamcr.2016.05.013. [Epub ahead of print] PMID: 27212270

CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis.
Margulieux KR, Fox JW, Nakamoto RK, Hughes MA. MBio. 2016 May 10;7(3). pii: e00334-16. doi: 10.1128/mBio.00334-16. PMID: 27165799

Proteomic identification of gender molecular markers in Bothrops jararaca venom.
Zelanis A, Menezes MC, Kitano ES, Liberato T, Tashima AK, Pinto AF, Sherman NE, Ho PL, Fox JW, Serrano SM. J Proteomics. 2016 Apr 29;139:26-37. doi: 10.1016/j.jprot.2016.02.030. Epub 2016 Mar 2. PMID: 26941108

Breast cancer antiestrogen resistance 3-p130^Cas interactions promote adhesion disassembly and invasion in breast cancer cells.
Cross AM, Wilson AL, Guerrero MS, Thomas KS, Bachir AI, Kubow KE, Horwitz AR, Bouton AH. Oncogene. 2016 Apr 25. doi: 10.1038/onc.2016.123. [Epub ahead of print] PMID: 27109104

State-of-the-art of regulatory dendritic cells in cancer.
Conejo-Garcia JR, Rutkowski MR, Cubillos-Ruiz JR. Pharmacol Ther. 2016 Apr 23. pii: S0163-7258(16)30043-2. doi: 10.1016/j.pharmthera.2016.04.003. [Epub ahead of print] Review. PMID: 27118338

Culture conditions tailored to the cell of origin are critical for maintaining native properties and tumorigenicity of glioma cells.
Ledur PF, Liu C, He H, Harris AR, Minussi DC, Zhou HY, Shaffrey ME, Asthagiri A, Lopes MB, Schiff D, Lu YC, Mandell JW, Lenz G, Zong H. Neuro Oncol. 2016 Apr 21. pii: now062. [Epub ahead of print] PMID: 27106408

A computational model of invasive aspergillosis in the lung and the role of iron.
Oremland M, Michels KR, Bettina AM, Lawrence C, Mehrad B, Laubenbacher R.
BMC Syst Biol. 2016 Apr 21;10(1):34. doi: 10.1186/s12918-016-0275-2.
PMID: 27098278

Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo.
Lee CS, Penberthy KK, Wheeler KM, Juncadella IJ, Vandenabeele P, Lysiak JJ, Ravichandran KS. Immunity. 2016 Apr 19;44(4):807-20. doi: 10.1016/j.immuni.2016.02.005. Epub 2016 Mar 29. PMID: 27037190

The state of melanoma: challenges and opportunities.
Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, Atkins MB, Bosenberg MW, Dummer R, Gershenwald JE, Halpern AC, Herlyn D, Karakousis GC, Kirkwood JM, Krauthammer M, Lo RS, Long GV, McArthur G, Ribas A, Schuchter L, Sosman JA, Smalley KS, Steeg P, Thomas NE, Tsao H, Tueting T, Weeraratna A, Xu G, Lomax R, Martin A, Silverstein S, Turnham T, Ronai ZA. Pigment Cell Melanoma Res. 2016 Apr 17. doi: 10.1111/pcmr.12475. [Epub ahead of print] PMID: 27087480

Characterization and in vitro activity of a branched peptide boronic acid that interacts with HIV-1 RRE RNA.
Wynn JE, Zhang W, Tebit DM, Gray LR, Hammarskjold ML, Rekosh D, Santos WL. Bioorg Med Chem. 2016 Apr 5. pii: S0968-0896(16)30243-7. doi: 10.1016/j.bmc.2016.04.009. [Epub ahead of print] PMID: 27091070

A large family of anti-activators accompanying XylS/AraC family regulatory proteins.
Santiago AE, Yan MB, Tran M, Wright N, Luzader DH, Kendall MM, Ruiz-Perez F, Nataro JP. Mol Microbiol. 2016 Apr 2. doi: 10.1111/mmi.13392. [Epub ahead of print] PMID: 27038276

Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis.
Herrera C, Macêdo JK, Feoli A, Escalante T, Rucavado A, Gutiérrez JM, Fox JW. PLoS Negl Trop Dis. 2016 Apr 1;10(4):e0004599. doi: 10.1371/journal.pntd.0004599. eCollection 2016 Apr. PMID: 27035343

NKp46(+) natural killer cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation in mice.
Tosello-Trampont AC, Krueger P, Narayanan S, Landes SG, Leitinger N, Hahn YS. Hepatology. 2016 Mar;63(3):799-812. doi: 10.1002/hep.28389. Epub 2016 Jan 21. PMID: 26662852

Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-γ Production by Altering Cellular Metabolism via Arginase-1.
Goh CC, Roggerson KM, Lee HC, Golden-Mason L, Rosen HR, Hahn YS. J Immunol. 2016 Mar 1;196(5):2283-92. doi: 10.4049/jimmunol.1501881. Epub 2016 Jan 29. PMID: 26826241

Molecular and Cellular Mechanisms of Shigella flexneri Dissemination.
Agaisse H. Front Cell Infect Microbiol. 2016 Mar 11;6:29. doi: 10.3389/fcimb.2016.00029. eCollection 2016. Review. PMID: 27014639

What a Dinner Party! Mechanisms and Functions of Interkingdom Signaling in Host-Pathogen Associations.
Kendall MM, Sperandio V. MBio. 2016 Mar 1;7(2). pii: e01748-15. doi: 10.1128/mBio.01748-15. Review. PMID: 26933054

T-Type Ca2+ Channel Inhibition Sensitizes Ovarian Cancer to Carboplatin.
Dziegielewska B, Casarez EV, Yang WZ, Gray LS, Dziegielewski J, Slack-Davis JK. Mol Cancer Ther. 2016 Mar;15(3):460-70. doi: 10.1158/1535-7163.MCT-15-0456. Epub 2016 Feb 1. PMID: 26832797

Location, location, location. Salmonella senses ethanolamine to gauge distinct host environments and coordinate gene expression
Christopher J. Anderson and Melissa M. Kendall
Microbial Cell, Vol. 3, No. 2, pp. 89 – 91; DOI: 10.15698/mic2016.02.479

Vancomycin Treatment Alters Humoral Immunity and Intestinal Microbiota in an Aged Mouse Model of Clostridium difficile Infection.
van Opstal E, Kolling GL, Moore JH 2nd, Coquery CM, Wade NS, Loo WM, Bolick DT, Shin JH, Erickson LD, Warren CA. J Infect Dis. 2016 Feb 24. pii: jiw071. [Epub ahead of print] PMID: 26917573

The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria.
Billings EA, Lee CS, Owen KA, D’Souza RS, Ravichandran KS, Casanova JE. Sci Signal. 2016 Feb 2;9(413):ra14. doi: 10.1126/scisignal.aac6250. PMID: 26838550

Commensal ‘trail of bread crumbs’ provide pathogens with a map to the intestinal landscape.
Luzader DH, Kendall MM. Curr Opin Microbiol. 2016 Feb;29:68-73. doi: 10.1016/j.mib.2015.11.005. Epub 2015 Dec 17. Review. PMID: 26707739

Genomic Modifiers of Natural Killer Cells, Immune Responsiveness and Lymphoid Tissue Remodeling Together Increase Host Resistance to Viral Infection.
Gillespie AL, Teoh J, Lee H, Prince J, Stadnisky MD, Anderson M, Nash W, Rival C, Wei H, Gamache A, Farber CR, Tung K, Brown MG.
PLoS Pathog. 2016 Feb 4;12(2):e1005419. doi: 10.1371/journal.ppat.1005419. eCollection 2016 Feb. PMID: 26845690

Salmonella Suppresses the TRIF-Dependent Type I Interferon Response in Macrophages.
Owen KA, Anderson CJ, Casanova JE.
MBio. 2016 Feb 16;7(1):e02051-15. doi: 10.1128/mBio.02051-15. PMID: 26884434

The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I.
Zhang Y, French SL, Beyer AL, Schneider DA.
J Biol Chem. 2016 Feb 5;291(6):3010-8. doi: 10.1074/jbc.M115.673442. Epub 2015 Dec 9.
PMID: 26663077 [PubMed – indexed for MEDLINE]

Ret and Etv4 Promote Directed Movements of Progenitor Cells during Renal Branching Morphogenesis.
Riccio P, Cebrian C, Zong H, Hippenmeyer S, Costantini F. PLoS Biol. 2016 Feb 19;14(2):e1002382. doi: 10.1371/journal.pbio.1002382. eCollection 2016 Feb. Erratum in: PLoS Biol. 2016 Jun;14(6):e1002488. PMID: 26894589

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas.
Roller DG, Capaldo B, Bekiranov S, Mackey AJ, Conaway MR, Petricoin EF, Gioeli D, Weber MJ. Oncotarget. 2016 Jan 19;7(3):2734-53. doi: 10.18632/oncotarget.6548. PMID: 26673621

Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses.
Baker LE, Ellena JF, Handing KB, Derewenda U, Utepbergenov D, Engel DA, Derewenda ZS. Acta Crystallogr D Struct Biol. 2016 Jan;72(Pt 1):49-58. doi: 10.1107/S2059798315021439. Epub 2016 Jan 1. PMID: 26894534

Interkingdom Chemical Signaling in Enterohemorrhagic Escherichia coli O157:H7.
Kendall MM. Adv Exp Med Biol. 2016;874:201-13. doi: 10.1007/978-3-319-20215-0_9. Review. PMID: 26589220

Delayed anaphylaxis to alpha-gal, an oligosaccharide in mammalian meat.
Commins SP, Jerath MR, Cox K, Erickson LD, Platts-Mills T. Allergol Int. 2016 Jan;65(1):16-20. doi: 10.1016/j.alit.2015.10.001. Epub 2015 Nov 21. Review. PMID: 26666477

Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity.
Farinha CM, Swiatecka-Urban A, Brautigan DL, Jordan P. Front Chem. 2016 Jan 20;4:1. doi: 10.3389/fchem.2016.00001. eCollection 2016. Review. PMID: 26835446

Apoptotic cell recognition receptors and scavenger receptors.
Penberthy KK, Ravichandran KS. Immunol Rev. 2016 Jan;269(1):44-59. doi: 10.1111/imr.12376. Review. PMID: 26683144

Antigenic Determinants of the Bilobal Cockroach Allergen Bla g 2.
Woodfolk JA, Glesner J, Wright PW, Kepley CL, Li M, Himly M, Muehling LM, Gustchina A, Wlodawer A, Chapman MD, Pomés A.
Biol Chem. 2016 Jan 29;291(5):2288-301. doi: 10.1074/jbc.M115.702324. Epub 2015 Dec 7. PMID: 26644466

Synergistic apoptosis in head and neck squamous cell carcinoma cells by co-inhibition of insulin-like growth factor-1 receptor signaling and compensatory signaling pathways.
Axelrod MJ, Mendez RE, Khalil A, Leimgruber SS, Sharlow ER, Capaldo B, Conaway M, Gioeli DG, Weber MJ, Jameson MJ.
Head Neck. 2015 Dec;37(12):1722-32. doi: 10.1002/hed.23822. Epub 2015 Apr 6.
PMID: 24986420

Integrative analysis to select cancer candidate biomarkers to targeted validation.
Kawahara R, Meirelles GV, Heberle H, Domingues RR, Granato DC, Yokoo S, Canevarolo RR, Winck FV, Ribeiro AC, Brandão TB, Filgueiras PR, Cruz KS, Barbuto JA, Poppi RJ, Minghim R, Telles GP, Fonseca FP, Fox JW, Santos-Silva AR, Coletta RD, Sherman NE, Paes Leme AF.
Oncotarget. 2015 Dec 22;6(41):43635-52. doi: 10.18632/oncotarget.6018. PMID:26540631

Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA.
Zboray L, Pluciennik A, Curtis D, Liu Y, Berman-Booty LD, Orr C, Kesler CT, Berger T, Gioeli D, Paschal BM, Merry DE.
Cell Rep. 2015 Dec 15;13(10):2312-23. doi: 10.1016/j.celrep.2015.11.019. Epub 2015 Dec 7. PMID: 26673324

Xanthophylls lutein and zeaxanthin modify gene expression and induce synthesis of hyaluronan in keratinocyte model of human skin.
Li, R, Turner, S.D. and Brautigan, D. L.
Biochemistry & Biophysics Reports 4: 52-58.(2015)

Small but Mighty: Selected Commensal Bacterial Species Determine the Effectiveness of Anti-cancer Immunotherapies.
Conejo-Garcia JR, Rutkowski MR.
Immunity. 2015 Dec 15;43(6):1037-9. doi: 10.1016/j.immuni.2015.11.014. PMID: 26682980

Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth.
Ta HQ, Ivey ML, Frierson HF Jr, Conaway MR, Dziegielewski J, Larner JM, Gioeli D.
Cancer Res. 2015 Dec 1;75(23):5093-105. doi: 10.1158/0008-5472.CAN-15-0224. Epub 2015 Nov 16. PMID: 26573794

Ethanolamine Signaling Promotes Salmonella Niche Recognition and Adaptation during Infection.
Anderson CJ, Clark DE, Adli M, Kendall MM.
PLoS Pathog. 2015 Nov 13;11(11):e1005278. doi: 10.1371/journal.ppat.1005278. eCollection 2015 Nov. Erratum in:PLoS Pathog. 2015 Dec;11(12):e1005365. PMID: 26565973

HIV-1 Group O Origin, Evolution, Pathogenesis, and Treatment: Unraveling the Complexity of an Outlier 25 Years Later.
Bush S, Tebit DM.
AIDS Rev. 2015 Jul-Sep;17(3):147-58.
PMID: 26450803

Defining the fitness of HIV-1 isolates with dual/mixed co-receptor usage.
Nankya IL, Tebit DM, Abraha A, Kyeyune F, Gibson R, Jegede O, Nickel G, Arts EJ.
AIDS Res Ther. 2015 Oct 3;12:34. doi: 10.1186/s12981-015-0066-7. eCollection 2015.
PMID: 26435727

Phagocytosis of apoptotic cells in homeostasis.
Arandjelovic S, Ravichandran KS.
Nat Immunol. 2015 Sep;16(9):907-17. doi: 10.1038/ni.3253. Review. PMID: 26287597

Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation.
Lohman AW, Leskov IL, Butcher JT, Johnstone SR, Stokes TA, Begandt D, DeLalio LJ, Best AK, Penuela S, Leitinger N, Ravichandran KS, Stokes KY, Isakson BE.
Nat Commun. 2015 Aug 5;6:7965. doi: 10.1038/ncomms8965. PMID: 26242575

Women at extreme risk for obesity-related carcinogenesis: Baseline endometrial pathology and impact of bariatric surgery on weight, metabolic profiles and quality of life.
Modesitt SC, Hallowell PT, Slack-Davis JK, Michalek RD, Atkins KA, Kelley SL, Arapovic S, Shupnik MA, Hoehn K.
Gynecol Oncol. 2015 Aug;138(2):238-45. doi: 10.1016/j.ygyno.2015.05.015. Epub 2015 May 23. PMID: 26013696

Hepcidin and Host Defense against Infectious Diseases.
Michels K, Nemeth E, Ganz T, Mehrad B.
PLoS Pathog. 2015 Aug 20;11(8):e1004998. doi: 10.1371/journal.ppat.1004998. eCollection 2015 Aug. Review. PMID:26291319

An improved method for differentiating cell-bound from internalized particles by imaging flow cytometry.
Smirnov A, Solga MD, Lannigan J, Criss AK.
J Immunol Methods. 2015 Aug;423:60-9. doi: 10.1016/j.jim.2015.04.028. Epub 2015 May 9. PMID: 25967947

The Bug Stops Here: Innate Lymphoid Cells in Clostridium difficile Infection.
Buonomo EL, Petri WA Jr.
Cell Host Microbe. 2015 Jul 8;18(1):5-6. doi: 10.1016/j.chom.2015.06.015. PMID:26159713

Analysis of cytokine production by peanut-reactive T cells identifies residual Th2 effectors in highly allergic children who received peanut oral immunotherapy.
Wisniewski JA, Commins SP, Agrawal R, Hulse KE, Yu MD, Cronin J, Heymann PW, Pomes A, Platts-Mills TA, Workman L, Woodfolk JA.
Clin Exp Allergy. 2015 Jul;45(7):1201-13. doi: 10.1111/cea.12537. PMID: 25823600

Editorial: NK cell reaping of Tfh cells: reckless slaughter or sensible pruning?
Brown MG, Erickson LD.
J Leukoc Biol. 2015 Aug;98(2):139-42. doi: 10.1189/jlb.4CE0415-175R. Epub 2015 Jun 5. No abstract available. PMID: 26048981

Exploring the role of environmental enteropathy in malnutrition, infant development and oral vaccine response.
Gilmartin AA, Petri WA Jr. Philos Trans R Soc Lond B
Biol Sci. 2015 Jun 19;370(1671). pii: 20140143. doi: 10.1098/rstb.2014.0143. Review. PMID:25964455

MEK2 is a prognostic marker and potential chemo-sensitizing target for glioma patients undergoing temozolomide treatment.
He H, Yao M, Zhang W, Tao B, Liu F, Li S, Dong Y, Zhang C, Meng Y, Li Y, Hu G, Luo C, Zong H, Lu Y.
Cell Mol Immunol. 2015 Jul 20. doi: 10.1038/cmi.2015.46. [Epub ahead of print] PMID: 26189368

B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis.
Rosenfeld SM, Perry HM, Gonen A, Prohaska TA, Srikakulapu P, Grewal S, Das D, McSkimming C, Taylor AM, Tsimikas S, Bender TP, Witztum JL, McNamara CA.
Circ Res. 2015 Jul 17;117(3):e28-39. doi: 10.1161/CIRCRESAHA.117.306044. Epub 2015 Jun 16. PMID: 26082558

A thermonuclease of Neisseria gonorrhoeae enhances bacterial escape from killing by neutrophil extracellular traps.
Juneau RA, Stevens JS, Apicella MA, Criss AK.
J Infect Dis. 2015 Jul 15;212(2):316-24. doi: 10.1093/infdis/jiv031. Epub 2015 Jan 20. PMID: 25605868

Chlamydiae interaction with the endoplasmic reticulum: contact, function and consequences.
Derré I.
Cell Microbiol. 2015 Jul;17(7):959-66. doi: 10.1111/cmi.12455. Epub 2015 May 27. Review. PMID: 25930206

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure.
Atkin-Smith GK, Tixeira R, Paone S, Mathivanan S, Collins C, Liem M, Goodall KJ, Ravichandran KS, Hulett MD, Poon IK.
Nat Commun. 2015 Jun 15;6:7439. doi: 10.1038/ncomms8439. PMID: 26074490

Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivo.
Lim SI, Hahn YS, Kwon I.
J Control Release. 2015 Jun 10;207:93-100. doi: 10.1016/j.jconrel.2015.04.004. Epub 2015 Apr 7. PMID: 25862515

The lipooligosaccharide-modifying enzyme LptA enhances gonococcal defence against human neutrophils.
Handing JW, Criss AK.
Cell Microbiol. 2015 Jun;17(6):910-21. doi: 10.1111/cmi.12411. Epub 2015 Feb 4. PMID: 25537831

Opa+ Neisseria gonorrhoeae exhibits reduced survival in human neutrophils via Src family kinase-mediated bacterial trafficking into mature phagolysosomes. Johnson MB, Ball LM, Daily KP, Martin JN, Columbus L, Criss AK.
Cell Microbiol. 2015 May;17(5):648-65. doi: 10.1111/cmi.12389. Epub 2014 Nov 25. PMID:25346239

The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication.
Sherpa C, Rausch JW, Le Grice SF, Hammarskjold ML, Rekosh D.
Nucleic Acids Res. 2015 May 19;43(9):4676-86. doi: 10.1093/nar/gkv313. Epub 2015 Apr 8. PMID: 25855816

Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity.
Peske JD, Thompson ED, Gemta L, Baylis RA, Fu YX, Engelhard VH.
Nat Commun. 2015 May 13;6:7114. doi: 10.1038/ncomms8114. PMID:  25968334

Cadherin-6B is required for the generation of Islet-1-expressing dorsal interneurons. Park KS,
Gumbiner BM.
Biochem Biophys Res Commun. 2015 Apr 10;459(3):504-8. doi: 10.1016/j.bbrc.2015.02.136. Epub 2015 Mar 5. PMID: 25747715

Liver-resident CD103+ dendritic cells prime antiviral CD8+ T cells in situ.
Krueger PD, Kim TS, Sung SS, Braciale TJ, Hahn YS.
J Immunol. 2015 Apr 1;194(7):3213-22. doi: 10.4049/jimmunol.1402622. Epub 2015 Feb 23. PMID:25712214

The “Performance of Rotavirus and Oral Polio Vaccines in Developing Countries” (PROVIDE) study: description of methods of an interventional study designed to explore complex biologic problems.
Kirkpatrick BD, Colgate ER, Mychaleckyj JC, Haque R, Dickson DM, Carmolli MP, Nayak U, Taniuchi M, Naylor C, Qadri F, Ma JZ, Alam M, Walsh MC, Diehl SA; PROVIDE Study Teams, Petri WAJr.
Am J Trop Med Hyg. 2015 Apr;92(4):744-51. doi: 10.4269/ajtmh.14-0518. Epub 2015 Feb 23. PMID: 25711607

Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction.
Rouhani SJ, Eccles JD, Riccardi P, Peske JD, Tewalt EF, Cohen JN, Liblau R, Mäkinen T, Engelhard VH.
Nat Commun. 2015 Apr 10;6:6771. doi: 10.1038/ncomms7771. PMID: 25857745

Cell-cycle-dependent regulation of androgen receptor function.
Koryakina Y, Knudsen KE, Gioeli D.
Endocr Relat Cancer. 2015 Apr;22(2):249-64. doi: 10.1530/ERC-14-0549. Epub 2015 Feb 17. PMID: 25691442

Liver-resident CD103+ dendritic cells prime antiviral CD8+ T cells in situ.
Krueger PD, Kim TS, Sung SS, Braciale TJ, Hahn YS.
J Immunol. 2015 Apr 1;194(7):3213-22. doi: 10.4049/jimmunol.1402622. Epub 2015 Feb 23. PMID: 25712214

ShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.
Trampont PC, Zhang L, Giles AJ, Walk SF, Gu JJ, Pendergast AM, Ravichandran KS.
Mol Cell Biol. 2015 Apr;35(8):1462-76. doi: 10.1128/MCB.01084-14. Epub 2015 Feb 17. PMID: 25691660

Mitochondrial control by DRP1 in brain tumor initiating cells.
Xie Q, Wu Q, Horbinski CM, Flavahan WA, Yang K, Zhou W, Dombrowski SM, Huang Z, Fang X, Shi Y, Ferguson AN, Kashatus DF, Bao S, Rich JN.
Nat Neurosci. 2015 Apr;18(4):501-10. doi: 10.1038/nn.3960. Epub 2015 Mar 2. PMID: 25730670

Tissue localization and extracellular matrix degradation by PI, PII and PIII snake venom metalloproteinases: clues on the mechanisms of venom-induced hemorrhage.
Herrera C, Escalante T, Voisin MB, Rucavado A, Morazán D, Macêdo JK, Calvete JJ, Sanz L, Nourshargh S, Gutiérrez JM, Fox JW.
PLoS Negl Trop Dis. 2015 Apr 24;9(4):e0003731. doi: 10.1371/journal.pntd.0003731. eCollection 2015 Apr. PMID: 25909592

RNA and lessons from viruses.
Hammarskjöld ML.
RNA. 2015 Apr;21(4):632-3. doi: 10.1261/rna.050310.115. No abstract available. PMID: 25780169

Evolutionary conservation of a molecular machinery for export and expression of mRNAs with retained introns.
Wang B, Rekosh D, Hammarskjold ML.
RNA. 2015 Mar;21(3):426-37. doi: 10.1261/rna.048520.114. Epub 2015 Jan 20. PMID: 25605961

A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells.
Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE.
Sci Signal. 2015 Feb 17;8(364):ra17. doi: 10.1126/scisignal.2005824. PMID: 25690012

ShcA regulates late stages of T cell development and peripheral CD4+ T cell numbers.
Buckley MW, Trampont PC, Arandjelovic S, Fond AM, Juncadella IJ, Ravichandran KS.
J Immunol. 2015 Feb 15;194(4):1665-76. doi: 10.4049/jimmunol.1401728. Epub 2015 Jan 16. PMID: 25595778

Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice.
Illendula A, Pulikkan JA, Zong H, Grembecka J, Xue L, Sen S, Zhou Y, Boulton A, Kuntimaddi A, Gao Y, Rajewski RA, Guzman ML, Castilla LH, Bushweller JH.
Science. 2015 Feb 13;347(6223):779-84. doi: 10.1126/science.aaa0314. PMID: 25678665

Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.
Kashatus JA, Nascimento A, Myers LJ, Sher A, Byrne FL, Hoehn KL, Counter CM, Kashatus DF.
Mol Cell. 2015 Feb 5;57(3):537-51. doi: 10.1016/j.molcel.2015.01.002. PMID: 25658205

Cell of origin for malignant gliomas and its implication in therapeutic development.
Zong H, Parada LF, Baker SJ.
Cold Spring Harb Perspect Biol. 2015 Jan 29;7(5). pii: a020610. doi: 10.1101/cshperspect.a020610. Review. PMID: 25635044

Cooperation between Noncanonical Ras Network Mutations.
Stites EC, Trampont PC, Haney LB, Walk SF, Ravichandran KS.
Cell Rep. 2015 Jan 15. pii: S2211-1247(14)01064-X. doi: 10.1016/j.celrep.2014.12.035. [Epub ahead of print] PMID: 25600866

Histone variants and epigenetics.
Henikoff S, Smith MM.
Cold Spring Harb Perspect Biol. 2015 Jan 5;7(1):a019364. doi: 10.1101/cshperspect.a019364. Review. PMID: 25561719

Control of CD8 T-Cell Infiltration into Tumors by Vasculature and Microenvironment.
Peske JD, Woods AB, Engelhard VH.
Adv Cancer Res. 2015;128:263-307. doi: 10.1016/bs.acr.2015.05.001. Epub 2015 Jun 1. Review. PMID: 26216636

Disintegrins from snake venoms and their applications in cancer research and therapy.
Arruda Macêdo JK, Fox JW, de Souza Castro M.
Curr Protein Pept Sci. 2015;16(6):532-48. Review. PMID: 26031306

Using phosphatidylserine exposure on apoptotic cells to stimulate myoblast fusion.
Hochreiter-Hufford AE, Arandjelovic S, Ravichandran KS. Methods Mol Biol. 2015;1313:141-8. doi: 10.1007/978-1-4939-2703-6_10. PMID: 25947662

Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma.
Capaldo BJ, Roller D, Axelrod MJ, Koeppel AF, Petricoin EF, Slingluff CL Jr, Weber MJ, Mackey AJ,Gioeli D, Bekiranov S.
PLoS One. 2015 Sep 25;10(9):e0138210. doi: 10.1371/journal.pone.0138210. eCollection 2015. PMID: 26405815

Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma.
Lee DH, Zhang Y, Kassam AB, Park MJ, Gardner P, Prevedello D, Henry S, Horbinski C, Beumer JH, Tawbi H, Williams BJ, Shaffrey ME, Egorin MJ, Abounader R, Park DM.
PLoS One. 2015 Aug 6;10(8):e0134426. doi: 10.1371/journal.pone.0134426. eCollection 2015. PMID: 26247786

Optical Imaging of Paramagnetic Bead-DNA Aggregation Inhibition Allows for Low Copy Number Detection of Infectious Pathogens.
DuVall JA, Borba JC, Shafagati N, Luzader D, Shukla N, Li J, Kehn-Hall K, Kendall MM, Feldman SH, Landers JP.
PLoS One. 2015 Jun 11;10(6):e0129830. doi: 10.1371/journal.pone.0129830. eCollection 2015. PMID: 26068926

Decreased peritoneal ovarian cancer growth in mice lacking expression of lipid phosphate phosphohydrolase 1.
Nakayama J, Raines TA, Lynch KR, Slack-Davis JK.
PLoS One. 2015 Mar 13;10(3):e0120071. doi: 10.1371/journal.pone.0120071. eCollection 2015. PMID: 25769037

BAFF regulates follicular helper t cells and affects their accumulation and interferon-γ production in autoimmunity.
Coquery CM, Loo WM, Wade NS, Bederman AG, Tung KS, Lewis JE, Hess H, Erickson LD.
Arthritis Rheumatol. 2015 Mar;67(3):773-84. doi: 10.1002/art.38950. PMID: 25385309

Legionella pneumophila utilizes a single-player disulfide-bond oxidoreductase system to manage disulfide bond formation and isomerization.
Kpadeh ZZ, Day SR, Mills BW, Hoffman PS.
Mol Microbiol. 2015 Mar;95(6):1054-69. doi: 10.1111/mmi.12914. Epub 2015 Jan 30. PMID: 25534767

Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining step.
Mingo RM, Simmons JA, Shoemaker CJ, Nelson EA, Schornberg KL, D’Souza RS, Casanova JE, White JM.
J Virol. 2015 Mar;89(5):2931-43. doi: 10.1128/JVI.03398-14. Epub 2014 Dec 31. PMID: 25552710

Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile.
Cowardin CA, Kuehne SA, Buonomo EL, Marie CS, Minton NP, Petri WA Jr.
MBio. 2015 Jan 27;6(1). pii: e02386-14. doi: 10.1128/mBio.02386-14. PMID:25626905

VCAM-1 on peritoneum and α4β1 integrin in endometrium and their implications in endometriosis.
Schutt AK, Atkins KA, Slack-Davis JK, Stovall DW.
Int J Gynecol Pathol. 2015 Jan;34(1):85-9. doi: 10.1097/PGP.0000000000000118.
PMID: 25473757