2017 Publications MIC Faculty and Students

Publications
CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer.
Michaels AD, Newhook TE, Adair SJ, Morioka S, Goudreau BJ, Nagdas S, Mullen MG, Persily JB, Bullock T, Slingluff CL, Ravichandran KS, Parsons JT, Bauer TW.
Clin Cancer Res. 2017 Dec 29. pii: clincanres.2283.2017. doi: 10.1158/1078-0432.CCR-17-2283. [Epub ahead of print]
PMID: 29288236
Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy.
Wilson RJ, Drake JC, Cui D, Zhang M, Perry HM, Kashatus JA, Kusminski CM, Scherer PE, Kashatus DF, Okusa MD, Yan Z.
Mitochondrion. 2017 Dec 20. pii: S1567-7249(17)30196-4. doi: 10.1016/j.mito.2017.12.008. [Epub ahead of print]
PMID: 29274400
Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation.
Cho J, Lim SI, Yang BS, Hahn YS, Kwon I.
Sci Rep. 2017 Dec 21;7(1):18041. doi: 10.1038/s41598-017-18029-y.
PMID: 29269881
Regulation of Transcription Factors by Reactive Oxygen Species and Nitric Oxide in Vascular Physiology and Pathology.
Kohlgrüber S, Upadhye A, Dyballa-Rukes N, McNamara CA, Altschmied J.
Antioxid Redox Signal. 2017 May 1;26(13):679-699. doi: 10.1089/ars.2016.6946. Epub 2017 Jan 4. Review.
PMID: 27841660
Noncoding RNAs in Glioblastoma.
Zhang Y, Cruickshanks N, Pahuski M, Yuan F, Dutta A, Schiff D, Purow B, Abounader R.
In: De Vleeschouwer S, editor.
Glioblastoma [Internet]. Brisbane (AU): Codon Publications; 2017 Sep 27.
PMID: 29251875
Rev-RRE Functional Activity Differs Substantially Among Primary HIV-1 Isolates.
Jackson PE, Tebit DM, Rekosh D, Hammarskjold ML.
AIDS Res Hum Retroviruses. 2016 Sep;32(9):923-34. doi: 10.1089/AID.2016.0047. Epub 2016 Jun 3.
PMID: 27147495
Editorial: Masters of fate: the APC cytokine milieu as a key regulator of distinct Tfh cell subsets.
Cox KM, Erickson LD.
J Leukoc Biol. 2017 Jan;101(1):1-3. doi: 10.1189/jlb.1CE0816-351R. No abstract available.
PMID: 28049141
Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone.
Good ME, Chiu YH, Poon IK, Medina CB, Butcher JT, Mendu SK, DeLalio LJ, Lohman AW, Leitinger N, Barrett EJ, Lorenz UM, Desai BN, Jaffe IZ, Bayliss D, Isakson BE, Ravichandran KS.
Circ Res. 2017 Dec 13. pii: CIRCRESAHA.117.312380. doi: 10.1161/CIRCRESAHA.117.312380. [Epub ahead of print]
PMID: 29237722
Identification of actin beta-like 2 (ACTBL2) as novel, upregulated protein in colorectal cancer.
Ghazanfar S, Fatima I, Aslam M, Musharraf SG, Sherman NE, Moskaluk C, Fox JW, Akhtar MW, Sadaf S.
J Proteomics. 2017 Jan 30;152:33-40. doi: 10.1016/j.jprot.2016.10.011. Epub 2016 Oct 27.
PMID: 27989943
A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice.
Tang F, Zhang P, Ye P, Lazarski CA, Wu Q, Bergin IL, Bender TP, Hall MN, Cui Y, Zhang L, Jiang T, Liu Y, Zheng P.
Elife. 2017 Dec 5;6. pii: e32497. doi: 10.7554/eLife.32497. [Epub ahead of print]
PMID: 29206103
Basic Research in Bacterial Pathogenesis: “What’s Your Job about, Exactly?”
Derré I.
PLoS Pathog. 2016 Oct 13;12(10):e1005612. doi: 10.1371/journal.ppat.1005612. eCollection 2016 Oct. No abstract available.
PMID: 27736976 [PubMed – indexed for MEDLINE] Free PMC Article
Context-dependent compensation among phosphatidylserine-recognition receptors.
Penberthy KK, Rival C, Shankman LS, Raymond MH, Zhang J, Perry JSA, Lee CS, Han CZ, Onengut-Gumuscu S, Palczewski K, Lysiak JJ, Ravichandran KS.
Sci Rep. 2017 Nov 7;7(1):14623. doi: 10.1038/s41598-017-15191-1.
PMID: 29116131
Zinc acquisition mechanisms differ between environmental and virulent Francisella species.
Moreau GB, Qin A, Mann BJ.
J Bacteriol. 2017 Nov 6. pii: JB.00587-17. doi: 10.1128/JB.00587-17. [Epub ahead of print]
PMID: 29109188
Differential expression of homing receptor ligands on tumor associated vasculature that control CD8 effector T cell entry.
Woods AN, Wilson AL, Srivinisan N, Zeng J, Dutta AB, Peske JD, Tewalt EF, Gregg RK, Ferguson AR, Engelhard VH.
Cancer Immunol Res. 2017 Nov 2. pii: canimm.0190.2017. doi: 10.1158/2326-6066.CIR-17-0190. [Epub ahead of print]
PMID: 29097419
Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway.
Rucavado A, Nicolau CA, Escalante T, Kim J, Herrera C, Gutiérrez JM, Fox JW.
Toxins (Basel). 2016 Nov 24;8(12). pii: E349.
PMID: 27886127
Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI.
Perry HM, Huang L, Wilson RJ, Bajwa A, Sesaki H, Yan Z, Rosin DL, Kashatus DF, Okusa MD.
J Am Soc Nephrol. 2017 Oct 30. pii: ASN.2017060659. doi: 10.1681/ASN.2017060659. [Epub ahead of print]
PMID: 29084809
IncV, a FFAT motif-containing Chlamydia protein, tethers the endoplasmic reticulum to the pathogen-containing vacuole.
Stanhope R, Flora E, Bayne C, Derré I.
Proc Natl Acad Sci U S A. 2017 Oct 23. pii: 201709060. doi: 10.1073/pnas.1709060114. [Epub ahead of print]
PMID: 29078338
Salmonella enterica Serovar Typhimurium Strategies for Host Adaptation.
Anderson CJ, Kendall MM.
Front Microbiol. 2017 Oct 12;8:1983. doi: 10.3389/fmicb.2017.01983. eCollection 2017. Review.
PMID: 29075247
Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.
Olmez I, Love S, Xiao A, Manigat L, Randolph P, McKenna BD, Neal BP, Boroda S, Li M, Brenneman B, Abounader R, Floyd D, Lee J, Nakano I, Godlewski J, Bronisz A, Sulman EP, Mayo M, Gioeli D, Weber M, Harris TE, Purow B.
Neuro Oncol. 2017 Jun 29. doi: 10.1093/neuonc/nox119.
Microenvironmental agonists generate <i>de novo</i> phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL.
Jayappa KD, Portell CA, Gordon VL, Capaldo BJ, Bekiranov S, Axelrod MJ, Brett LK, Wulfkuhle JD, Gallagher RI, Petricoin EF, Bender TP, Williams ME, Weber MJ.
Blood Adv. 2017 Jun 13;1(14):933-946.
PMID: 29034364 [PubMed]
Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract: neutrophilic host response, sustained infection, and clinical sequelae.
Stevens JS, Criss AK.
Curr Opin Hematol. 2017 Oct 7. doi: 10.1097/MOH.0000000000000394. [Epub ahead of print]
PMID: 29016383
The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state.
Llewellyn RA, Thomas KS, Gutknecht MF, Bouton AH.
J Leukoc Biol. 2017 Oct;102(4):1069-1080. doi: 10.1189/jlb.1A0217-063R. Epub 2017 Jul 28.
PMID: 28754799
Culture conditions defining glioblastoma cells behavior: what is the impact for novel discoveries?
Ledur PF, Onzi GR, Zong H, Lenz G.
Oncotarget. 2017 Aug 11;8(40):69185-69197. doi: 10.18632/oncotarget.20193. eCollection 2017 Sep 15. Review.
PMID: 28978189
Neisseria: recent advances and future challenges.
Criss A, Tang C.
Pathog Dis. 2017 Nov 30;75(8). doi: 10.1093/femspd/ftx090. No abstract available.
PMID: 28957453
The Use of the Woodchuck as an Animal Model for Evaluation of Transarterial Embolization.
Wilkins LR, Stone JR, Mata J, Hawrylack A, Kubicka E, Brautigan DL.
J Vasc Interv Radiol. 2017 Oct;28(10):1467-1471. doi: 10.1016/j.jvir.2017.04.005.
PMID: 28941521
Th1 Signatures Are Present in the Lower Airways of Children with Severe Asthma, Regardless of Allergic Status.
Wisniewski JA, Muehling LM, Eccles JD, Capaldo BJ, Agrawal R, Shirley DA, Patrie JT, Workman LJ, Schuyler AJ, Lawrence MG, Teague WG, Woodfolk JA.
J Allergy Clin Immunol. 2017 Sep 19. pii: S0091-6749(17)31463-X. doi: 10.1016/j.jaci.2017.08.020. [Epub ahead of print]
PMID: 28939412
From bacterial killing to immune modulation: Recent insights into the functions of lysozyme.
Ragland SA, Criss AK.
PLoS Pathog. 2017 Sep 21;13(9):e1006512. doi: 10.1371/journal.ppat.1006512. eCollection 2017 Sep. Review.
PMID: 28934357
Characterization and in vitro activity of a branched peptide boronic acid that interacts with HIV-1 RRE RNA.
Wynn JE, Zhang W, Tebit DM, Gray LR, Hammarskjold ML, Rekosh D, Santos WL.
Bioorg Med Chem. 2016 Sep 1;24(17):3947-3952. doi: 10.1016/j.bmc.2016.04.009. Epub 2016 Apr 5.
PMID: 27091070
Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Dolina JS, Cechova S, Rudy CK, Sung SJ, Tang WW, Lee J, Hahn YS, Le TH.
J Immunol. 2017 Mar 15;198(6):2341-2351. doi: 10.4049/jimmunol.1502234. Epub 2017 Feb 3.
PMID: 28159899
The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Mohammed F, Stones DH, Zarling AL, Willcox CR, Shabanowitz J, Cummings KL, Hunt DF, Cobbold M, Engelhard VH, Willcox BE.
Oncotarget. 2017 Apr 8;8(33):54160-54172. doi: 10.18632/oncotarget.16952. eCollection 2017 Aug 15.
PMID: 28903331
SUMO and Chromatin Remodeling.
Wotton D, Pemberton LF, Merrill-Schools J.
Adv Exp Med Biol. 2017;963:35-50. doi: 10.1007/978-3-319-50044-7_3. Review.
PMID: 28197905
An NXF1 mRNA with a retained intron is expressed in hippocampal and neocortical neurons and is translated into a protein that functions as an Nxf1 cofactor.
Li Y, Bor YC, Fitzgerald MP, Lee KS, Rekosh D, Hammarskjold ML.
Mol Biol Cell. 2016 Dec 1;27(24):3903-3912. Epub 2016 Oct 5.
PMID: 27708137
Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.
Bukrejewska M, Derewenda U, Radwanska M, Engel DA, Derewenda ZS.
Acta Crystallogr D Struct Biol. 2017 Sep 1;73(Pt 9):767-774. doi: 10.1107/S2059798317010737. Epub 2017 Aug 15.
PMID: 28876240
Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells.
Krueger PD, Narayanan S, Surette FA, Brown MG, Sung SJ, Hahn YS.
J Leukoc Biol. 2017 Jan;101(1):329-338. doi: 10.1189/jlb.3A0516-225R. Epub 2016 Aug 4.
PMID: 27493244
Cardiolipin Synthesis and Outer Membrane Localization Are Required for Shigella flexneri Virulence.
Rossi RM, Yum L, Agaisse H, Payne SM.
MBio. 2017 Aug 29;8(4). pii: e01199-17. doi: 10.1128/mBio.01199-17.
PMID: 28851846
Inhibition of Amebic Lysosomal Acidification Blocks Amebic Trogocytosis and Cell Killing.
Gilmartin AA, Ralston KS, Petri WA Jr.
MBio. 2017 Aug 29;8(4). pii: e01187-17. doi: 10.1128/mBio.01187-17.
PMID: 28851845
Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells.
Penberthy KK, Buckley MW, Arandjelovic S, Ravichandran K.
PLoS One. 2017 Mar 7;12(3):e0173386. doi: 10.1371/journal.pone.0173386. eCollection 2017.
PMID: 28267764
‘This way please’: Apoptotic cells regulate phagocyte migration before and after engulfment.
Ariel A, Ravichandran KS.
Eur J Immunol. 2016 Jul;46(7):1583-6. doi: 10.1002/eji.201646505. Epub 2016 Jun 27.
PMID: 27345468
Combined CDK4/6 and mTOR inhibition is synergistic against glioblastoma via multiple mechanisms.
Olmez I, Brenneman B, Xiao A, Serbulea V, Benamar M, Zhang Y, Manigat L, Abbas T, Lee J, Nakano I, Godlewski J, Bronisz A, Abounader R, Leitinger N, Purow B.
Clin Cancer Res. 2017 Aug 16. pii: clincanres.0803.2017. doi: 10.1158/1078-0432.CCR-17-0803. [Epub ahead of print]
PMID: 28814434
Hijacking of Membrane Contact Sites by Intracellular Bacterial Pathogens.
Derré I.
Adv Exp Med Biol. 2017;997:211-223. doi: 10.1007/978-981-10-4567-7_16.
PMID: 28815533
Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice.
Sung SJ, Ge Y, Dai C, Wang H, Fu SM, Sharma R, Hahn YS, Yu J, Le TH, Okusa MD, Bolton WK, Lawler JR.
J Immunol. 2017 Apr 1;198(7):2589-2601. doi: 10.4049/jimmunol.1601565. Epub 2017 Feb 20.
PMID: 28219886
The AraC Negative Regulator family modulates the activity of histone-like proteins in pathogenic bacteria.
Santiago AE, Yan MB, Hazen TH, Sauder B, Meza-Segura M, Rasko DA, Kendall MM, Ruiz-Perez F, Nataro JP.
PLoS Pathog. 2017 Aug 14;13(8):e1006545. doi: 10.1371/journal.ppat.1006545. [Epub ahead of print]
PMID: 28806780
Two lytic transglycosylases in Neisseria gonorrhoeae impart resistance to killing by lysozyme and human neutrophils.
Ragland SA, Schaub RE, Hackett KT, Dillard JP, Criss AK.
Cell Microbiol. 2017 Mar;19(3). doi: 10.1111/cmi.12662. Epub 2016 Nov 3.
PMID: 27597434
Expression of scavenger receptor-AI promotes alternative activation of murine macrophages to limit hepatic inflammation and fibrosis.
Labonte AC, Sung SJ, Jennelle LT, Dandekar AP, Hahn YS.
Hepatology. 2017 Jan;65(1):32-43. doi: 10.1002/hep.28873. Epub 2016 Nov 22.
PMID: 27770558
Vaccines targeting helper T cells for cancer immunotherapy.
Melssen M, Slingluff CL Jr.
Curr Opin Immunol. 2017 Jul 26;47:85-92. doi: 10.1016/j.coi.2017.07.004. [Epub ahead of print] Review.
PMID: 28755541
The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state.
Llewellyn RA, Thomas KS, Gutknecht MF, Bouton AH.
J Leukoc Biol. 2017 Jul 28. pii: jlb.1A0217-063R. doi: 10.1189/jlb.1A0217-063R. [Epub ahead of print]
PMID: 28754799
High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa.
Etta EM, Mavhandu L, Manhaeve C, McGonigle K, Jackson P, Rekosh D, Hammarskjold ML, Bessong PO, Tebit DM.
AIDS Res Ther. 2017 Jul 27;14(1):36. doi: 10.1186/s12981-017-0161-z.
PMID: 28750647
Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during HCV infection.
Cobb DA, Golden-Mason L, Rosen HR, Hahn YS.
Hepatology. 2017 Jul 27. doi: 10.1002/hep.29409. [Epub ahead of print]
PMID: 28749570
Distinct Roles for Intracellular and Extracellular Lipids in Hepatitis C Virus Infection.
Narayanan S, Nieh AH, Kenwood BM, Davis CA, Tosello-Trampont AC, Elich TD, Breazeale SD, Ward E, Anderson RJ, Caldwell SH, Hoehn KL, Hahn YS.
PLoS One. 2016 Jun 9;11(6):e0156996. doi: 10.1371/journal.pone.0156996. eCollection 2016.
PMID: 27280294
Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes.
Shah M, Smolko CM, Kinicki S, Chapman ZD, Brautigan DL, Janes KA.
Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S244-S262. doi: 10.1074/mcp.O116.063487. Epub 2017 Feb 7.
PMID: 28174228
Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance.
Carey MA, Papin JA, Guler JL.
BMC Genomics. 2017 Jul 19;18(1):543. doi: 10.1186/s12864-017-3905-1.
PMID: 28724354
MEK2 is a prognostic marker and potential chemo-sensitizing target for glioma patients undergoing temozolomide treatment.
He H, Yao M, Zhang W, Tao B, Liu F, Li S, Dong Y, Zhang C, Meng Y, Li Y, Hu G, Luo C, Zong H, Lu Y.
Cell Mol Immunol. 2016 Sep;13(5):658-68. doi: 10.1038/cmi.2015.46. Epub 2015 Jul 20.
PMID: 26189368
CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis.
Margulieux KR, Fox JW, Nakamoto RK, Hughes MA.
MBio. 2016 May 10;7(3). pii: e00334-16. doi: 10.1128/mBio.00334-16.
PMID: 27165799
Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma.
Cruickshanks N, Zhang Y, Yuan F, Pahuski M, Gibert M, Abounader R.
Cancers (Basel). 2017 Jul 11;9(7). pii: E87. doi: 10.3390/cancers9070087. Review.
PMID: 28696366
The influence of the commensal microbiota on distal tumor-promoting inflammation.
Buchta Rosean CM, Rutkowski MR.
Semin Immunol. 2017 Jul 4. pii: S1044-5323(17)30019-2. doi: 10.1016/j.smim.2017.06.002. [Epub ahead of print] Review.
PMID: 28687194
The regulation of tumor cell physiology by mitochondrial dynamics.
Kashatus DF.
Biochem Biophys Res Commun. 2017 Jul 1. pii: S0006-291X(17)31323-2. doi: 10.1016/j.bbrc.2017.06.192. [Epub ahead of print]
PMID: 28676396
Detection and Quantification of Mitochondrial Fusion Using Imaging Flow Cytometry.
Nascimento A, Lannigan J, Kashatus D.
Curr Protoc Cytom. 2017 Jul 5;81:9.53.1-9.53.13. doi: 10.1002/cpcy.26.
PMID: 28678419
Functions of protein phosphatase-6 in NF-κB signaling and in lymphocytes.
Ziembik MA, Bender TP, Larner JM, Brautigan DL.
Biochem Soc Trans. 2017 Jun 15;45(3):693-701. doi: 10.1042/BST20160169. Review.
PMID: 28620030
A conserved leucine zipper motif in gammaherpesvirus ORF52 is critical for distinct microtubule rearrangements.
Loftus MS, Verville N, Kedes DH.
J Virol. 2017 Jun 14. pii: JVI.00304-17. doi: 10.1128/JVI.00304-17. [Epub ahead of print]
PMID: 28615210
SR proteins: To shuttle or not to shuttle, that is the question.
Hammarskjold ML, Rekosh D.
J Cell Biol. 2017 Jun 9. pii: jcb.201705009. doi: 10.1083/jcb.201705009. [Epub ahead of print]
PMID: 28600433
Adhesion GPCRs as Modulators of Immune Cell Function.
Hamann J, Hsiao CC, Lee CS, Ravichandran KS, Lin HH.
Handb Exp Pharmacol. 2016;234:329-350. Review.
PMID: 27832495
Symmetry breaking in spreading RAT2 fibroblasts requires the MAPK/ERK pathway scaffold RACK1 that integrates FAK, p190A-RhoGAP and ERK2 signaling.
Klímová Z, Bráborec V, Maninová M, Čáslavský J, Weber MJ, Vomastek T.
Biochim Biophys Acta. 2016 Sep;1863(9):2189-200. doi: 10.1016/j.bbamcr.2016.05.013. Epub 2016 May 19.
PMID: 27212270
Mesothelium expression of vascular cell adhesion molecule-1 (VCAM-1) is associated with an unfavorable prognosis in epithelial ovarian cancer (EOC).
Scalici JM, Arapovic S, Saks EJ, Atkins KA, Petroni G, Duska LR, Slack-Davis JK.
Cancer. 2017 May 15;123(6):977-984. doi: 10.1002/cncr.30415. Epub 2016 Nov 7.
PMID: 28263384
T Cells Deficient in the Tyrosine Phosphatase SHP-1 Resist Suppression by Regulatory T Cells.
Mercadante ER, Lorenz UM.
J Immunol. 2017 May 26. pii: 1602171. doi: 10.4049/jimmunol.1602171. [Epub ahead of print]
PMID: 28550200
Neisseria gonorrhoeae Evades Calprotectin-Mediated Nutritional Immunity and Survives Neutrophil Extracellular Traps by Production of TdfH.
Jean S, Juneau RA, Criss AK, Cornelissen CN.
Infect Immun. 2016 Sep 19;84(10):2982-94. doi: 10.1128/IAI.00319-16. Print 2016 Oct.
PMID: 27481245
Aurora Kinase A Promotes AR Degradation via the E3 Ligase CHIP.
Larner JM, Sarkar S, Brautigan DL.
Mol Cancer Res. 2017 May 23. pii: molcanres.0062.2017. doi: 10.1158/1541-7786.MCR-17-0062. [Epub ahead of print]
PMID: 28536143 [PubMed – as supplied by publisher]
IL233, A Novel IL-2 and IL-33 Hybrid Cytokine, Ameliorates Renal injury.
Stremska ME, Jose S, Sabapathy V, Huang L, Bajwa A, Kinsey GR, Sharma PR, Mohammad S, Rosin DL, Okusa MD, Sharma R.
J Am Soc Nephrol. 2017 May 24. pii: ASN.2016121272. doi: 10.1681/ASN.2016121272. [Epub ahead of print]
PMID: 28539382
Role of Serum Amyloid A, Granulocyte-Macrophage Colony-Stimulating Factor, and Bone Marrow Granulocyte-Monocyte Precursor Expansion in Segmented Filamentous Bacterium-Mediated Protection from Entamoeba histolytica.
Burgess SL, Saleh M, Cowardin CA, Buonomo E, Noor Z, Watanabe K, Abhyankar M, Lajoie S, Wills-Karp M, Petri WA Jr.
Infect Immun. 2016 Sep 19;84(10):2824-32. doi: 10.1128/IAI.00316-16. Print 2016 Oct.
PMID: 27456830
Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis.
Reon BJ, Anaya J, Zhang Y, Mandell J, Purow B, Abounader R, Dutta A.
PLoS Med. 2016 Dec 6;13(12):e1002192. doi: 10.1371/journal.pmed.1002192. eCollection 2016 Dec.
PMID: 27923049
Vancomycin Treatment Alters Humoral Immunity and Intestinal Microbiota in an Aged Mouse Model of Clostridium difficile Infection.
van Opstal E, Kolling GL, Moore JH 2nd, Coquery CM, Wade NS, Loo WM, Bolick DT, Shin JH, Erickson LD, Warren CA.
J Infect Dis. 2016 Jul 1;214(1):130-9. doi: 10.1093/infdis/jiw071. Epub 2016 Feb 24.
PMID: 26917573
The Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics.
Nagdas S, Kashatus DF.
Antioxidants (Basel). 2017 May 17;6(2). pii: E33. doi: 10.3390/antiox6020033. Review.
PMID: 28513539
Targetable T-type calcium channels drive glioblastoma.
Zhang Y, Cruickshanks N, Yuan F, Wang B, Pahuski M, Wulfkuhle J, Gallagher I, Koeppel AF, Hatef S, Papanicolas C, Lee J, Bar EE, Schiff D, Turner S, Petricoin EF, Gray LS, Abounader R.
Cancer Res. 2017 May 16. pii: canres.2347.2016. doi: 10.1158/0008-5472.CAN-16-2347. [Epub ahead of print]
PMID: 28512247
Lineage-Specific Metabolic Properties and Vulnerabilities of T Cells in the Demyelinating Central Nervous System.
Seki SM, Stevenson M, Rosen AM, Arandjelovic S, Gemta L, Bullock TNJ, Gaultier A.
J Immunol. 2017 May 15. pii: 1600825. doi: 10.4049/jimmunol.1600825. [Epub ahead of print]
PMID: 28507026
Restarting Lytic Gene Transcription at the Onset of Herpes Simplex Virus Reactivation.
Cliffe AR, Wilson AC.
J Virol. 2017 Jan 3;91(2). pii: e01419-16. doi: 10.1128/JVI.01419-16. Print 2017 Jan 15. Review.
PMID: 27807236
The Type Three Secretion System 2-Encoded Regulator EtrB Modulates Enterohemorrhagic Escherichia coli Virulence Gene Expression.
Luzader DH, Willsey GG, Wargo MJ, Kendall MM.
Infect Immun. 2016 Aug 19;84(9):2555-65. doi: 10.1128/IAI.00407-16. Print 2016 Sep.
PMID: 27324484
Bacillus anthracis Peptidoglycan Integrity Is Disrupted by the Chemokine CXCL10 through the FtsE/X Complex.
Margulieux KR, Liebov BK, Tirumala VSKKS, Singh A, Bushweller JH, Nakamoto RK, Hughes MA.
Front Microbiol. 2017 Apr 27;8:740. doi: 10.3389/fmicb.2017.00740. eCollection 2017.
PMID: 28496437
Neisserial Opa Protein-CEACAM Interactions: Competition for Receptors as a Means of Bacterial Invasion and Pathogenesis.
Martin JN, Ball LM, Solomon TL, Dewald AH, Criss AK, Columbus L.
Biochemistry. 2016 Aug 9;55(31):4286-94. doi: 10.1021/acs.biochem.6b00124. Epub 2016 Aug 1.
PMID: 27442026
Cinnamic Acid Derivatives Enhance the Efficacy of Transarterial Embolization in a Rat Model of Hepatocellular Carcinoma.
Wilkins LR, Brautigan DL, Wu H, Yarmohammadi H, Kubicka E, Serbulea V, Leitinger N, Liu W, Haaga JR.
Cardiovasc Intervent Radiol. 2017 Mar;40(3):430-437. doi: 10.1007/s00270-016-1515-y. Epub 2016 Nov 21.
PMID: 27872984 [PubMed – indexed for MEDLINE]
Extra! Extracellular Effector Delivery into Host Cells via the Type 3 Secretion System.
Kendall MM.
MBio. 2017 May 2;8(3). pii: e00594-17. doi: 10.1128/mBio.00594-17.
PMID: 28465427
Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.
Kim DW, Wu N, Kim YC, Cheng PF, Basom R, Kim D, Dunn CT, Lee AY, Kim K, Lee CS, Singh A, Gazdar AF, Harris CR, Eisenman RN, Park KS, MacPherson D.
Genes Dev. 2016 Jun 1;30(11):1289-99. doi: 10.1101/gad.279307.116.
PMID: 27298335
The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Mohammed F, Stones DH, Zarling AL, Willcox CR, Shabanowitz J, Cummings KL, Hunt DF, Cobbold M, Engelhard VH, Willcox BE.
Oncotarget. 2017 Apr 8. doi: 10.18632/oncotarget.16952.
PMID: 28446731
Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.
Kim DW, Wu N, Kim YC, Cheng PF, Basom R, Kim D, Dunn CT, Lee AY, Kim K, Lee CS, Singh A, Gazdar AF, Harris CR, Eisenman RN, Park KS, MacPherson D.
Genes Dev. 2016 Jun 1;30(11):1289-99. doi: 10.1101/gad.279307.116.
PMID: 27298335
Lysolecithin as feed additive enhances collagen expression and villus length in the jejunum of broiler chickens.
Brautigan DL, Li R, Kubicka E, Turner SD, Garcia JS, Weintraut ML, Wong EA.
Poult Sci. 2017 Apr 24. doi: 10.3382/ps/pex078.
PMID: 28444343
Pathogenic CD4<sup>+</sup> T cells in patients with asthma.
Muehling LM, Lawrence MG, Woodfolk JA.
J Allergy Clin Immunol. 2017 Apr 22. pii: S0091-6749(17)30422-0. doi: 10.1016/j.jaci.2017.02.025. [Epub ahead of print] Review.
PMID: 28442213
CD11c-Expressing Cells Affect Regulatory T Cell Behavior in the Meninges during Central Nervous System Infection.
O’Brien CA, Overall C, Konradt C, O’Hara Hall AC, Hayes NW, Wagage S, John B, Christian DA, Hunter CA, Harris TH.
J Immunol. 2017 Apr 7. pii: 1601581. doi: 10.4049/jimmunol.1601581. [Epub ahead of print]
PMID: 28389591
Immunoregulatory Role of NK Cells in Tissue Inflammation and Regeneration.
Tosello-Trampont A, Surette FA, Ewald SE, Hahn YS.
Front Immunol. 2017 Mar 20;8:301. doi: 10.3389/fimmu.2017.00301. eCollection 2017. Review.
PMID: 28373874
High-Throughput Particle Uptake Analysis by Imaging Flow Cytometry.
Smirnov A, Solga MD, Lannigan J, Criss AK.
Curr Protoc Cytom. 2017 Apr 3;80:11.22.1-11.22.17. doi: 10.1002/cpcy.19.
PMID: 28369762
Oncogenic effects of evolutionarily conserved noncoding RNA ECONEXIN on gliomagenesis.
Deguchi S, Katsushima K, Hatanaka A, Shinjo K, Ohka F, Wakabayashi T, Zong H, Natsume A, Kondo Y.
Oncogene. 2017 Apr 3. doi: 10.1038/onc.2017.88.
PMID: 28368417
A Co-infection Model System and the Use of Chimeric Proteins to Study <i>Chlamydia</i> Inclusion Proteins Interaction.
Han Y, Derré I.
Front Cell Infect Microbiol. 2017 Mar 14;7:79. doi: 10.3389/fcimb.2017.00079. eCollection 2017 Mar 14.
PMID: 28352612
Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia.
Michels KR, Zhang Z, Bettina AM, Cagnina RE, Stefanova D, Burdick MD, Vaulont S, Nemeth E, Ganz T, Mehrad B.
JCI Insight. 2017 Mar 23;2(6):e92002. doi: 10.1172/jci.insight.92002.
PMID: 28352667
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation.
Han CZ, Juncadella IJ, Kinchen JM, Buckley MW, Klibanov AL, Dryden K, Onengut-Gumuscu S, Erdbrügger U, Turner SD, Shim YM, Tung KS, Ravichandran KS.
Nature. 2016 Nov 24;539(7630):570-574. doi: 10.1038/nature20141. Epub 2016 Nov 7.
PMID: 27820945
Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis.
Noor Z, Watanabe K, Abhyankar MM, Burgess SL, Buonomo EL, Cowardin CA, Petri WA Jr.
MBio. 2017 Feb 28;8(1). pii: e02329-16. doi: 10.1128/mBio.02329-16.
PMID: 28246365
Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia.
Ramakrishnan G, Wright M, Alam M, Naylor C, Kabir M, Zerin A, Ferdous T, Pedersen K, Hennig BJ, Donowitz JR, Wegmuller R, Haque R, Petri WA Jr, Herbein J, Gilchrist CA.
Diagn Microbiol Infect Dis. 2017 Mar;87(3):272-274. doi: 10.1016/j.diagmicrobio.2016.11.011.
PMID: 27916543
Understanding the Snake Venom Metalloproteinases: An Interview with Jay Fox and José María Gutiérrez.
Fox JW, Gutiérrez JM.
Toxins (Basel). 2017 Jan 16;9(1). pii: E33. doi: 10.3390/toxins9010033.
PMID: 28275208
Lysophosphatidic acid counteracts glucagon-induced hepatocyte glucose production via STAT3.
Taddeo EP, Hargett SR, Lahiri S, Nelson ME, Liao JA, Li C, Slack-Davis JK, Tomsig JL, Lynch KR, Yan Z, Harris TE, Hoehn KL.
Sci Rep. 2017 Dec;7(1):127. doi: 10.1038/s41598-017-00210-y.
PMID: 28273928
Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells.
Penberthy KK, Buckley MW, Arandjelovic S, Ravichandran K.
PLoS One. 2017 Mar 7;12(3):e0173386. doi: 10.1371/journal.pone.0173386.
PMID: 28267764
Mesothelium expression of vascular cell adhesion molecule-1 (VCAM-1) is associated with an unfavorable prognosis in epithelial ovarian cancer (EOC).
Scalici JM, Arapovic S, Saks EJ, Atkins KA, Petroni G, Duska LR, Slack-Davis JK.
Cancer. 2017 May 15;123(6):977-984. doi: 10.1002/cncr.30415.
PMID: 28263384
Herpes Simplex Virus Latency: The DNA Repair-Centered Pathway.
Brown JC.
Adv Virol. 2017;2017:7028194. doi: 10.1155/2017/7028194. Review.
PMID: 28255301
The E3 Ligase CHIP Mediates p21 Degradation to Maintain Radioresistance.
Biswas K, Sarkar S, Du K, Brautigan DL, Abbas T, Larner JM.
Mol Cancer Res. 2017 Feb 23. pii: molcanres.0466.2016. doi: 10.1158/1541-7786.MCR-16-0466. [Epub ahead of print]
PMID: 28232384
SUMO and Chromatin Remodeling.
Wotton D, Pemberton LF, Merrill-Schools J.
Adv Exp Med Biol. 2017;963:35-50. doi: 10.1007/978-3-319-50044-7_3.
PMID: 28197905
Hematopoietic pannexin 1 function is critical for neuropathic pain.
Weaver JL, Arandjelovic S, Brown G, K Mendu S, S Schappe M, Buckley MW, Chiu YH, Shu S, Kim JK, Chung J, Krupa J, Jevtovic-Todorovic V, Desai BN, Ravichandran KS, Bayliss DA.
Sci Rep. 2017 Feb 14;7:42550. doi: 10.1038/srep42550.
PMID: 28195232
Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers.
Illendula A, Gilmour J, Grembecka J, Tirumala VS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, Mishra L, Adli M, Castilla LH, Rajewski RA, Janes KA, Guzman ML, Bonifer C, Bushweller JH.
EBioMedicine. 2016 Jun;8:117-31. doi: 10.1016/j.ebiom.2016.04.032.
PMID: 27428424
Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.
Benamar M, Guessous F, Du K, Corbett P, Obeid J, Gioeli D, Slingluff CL Jr, Abbas T.
EBioMedicine. 2016 Aug;10:85-100. doi: 10.1016/j.ebiom.2016.06.023.
PMID: 27333051
Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes.
Shah M, Smolko CM, Kinicki S, Chapman ZD, Brautigan DL, Janes KA.
Mol Cell Proteomics. 2017 Feb 7. pii: mcp.O116.063487. doi: 10.1074/mcp.O116.063487. [Epub ahead of print]
PMID: 28174228
Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Dolina JS, Cechova S, Rudy CK, Sung SJ, Tang WW, Lee J, Hahn YS, Le TH.
J Immunol. 2017 Feb 3. pii: 1502234. doi: 10.4049/jimmunol.1502234.
PMID: 28159899
Editorial: Masters of fate: the APC cytokine milieu as a key regulator of distinct Tfh cell subsets.
Cox KM, Erickson LD.
J Leukoc Biol. 2017 Jan;101(1):1-3. doi: 10.1189/jlb.1CE0816-351R. No abstract available.
PMID: 28049141