Basic and translational brain tumor research
Genetic approaches, cellular and molecular biology of intracellular pathogen infection
Regulation of gene expression during lymphocyte development
Signaling Pathways that Regulate Tumor Growth, Metastasis, and Response to Anticancer Agents; Adhesion Signaling In Macrophages; Bacteria-Host Cell Interactions.
Protein Phosphorylation in Cell Signaling
Structure and Assembly of the Herpes Simplex Virus Capsid.
Herpes simplex virus infection of neurons
Cellular and molecular mechanisms of Neisserial pathogenesis
Host/pathogen Interaction - Chlamydia Infection
Tumor microenvironment and mechanisms of tumor neovascularization
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Influenza, Dengue and Ebola.
Identification of MHC-restricted tumor antigens / Control of T cell homing to tumors / Role of lymphatic endothelial cells in regulating immunity and self-tolerance
Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders
Innate immunity, chronic disease, host-parasite interactions
Basement Membrane Structure and Metalloproteinases
Signal transduction in cancer cells
Immune regulation for HCV infection and chronic liver inflammation
Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
Human Herpes virus associated with malignancy, including Kaposi's Sarcoma
Mechanisms used by Bacterial Pathogens to Integrate Host- and Bacterial-derived Signals to Sense their Environment, Coordinate Gene Expression, and Cause Disease
Involvement of the protein tyrosine phosphatase SHP-1 in signal transduction pathways
Mechanisms of tumor progression and homeostasis
Nuclear Transport in Chromatin Assembly and Transcriptional Regulation
Apoptotic cell clearance mechanisms in health and disease
Human Immunodeficiency; Virus Gene Expression
Influence of commensal microbes on immune homeostasis, anti-tumor immunity, and metastasis
Functional Genomics of Histones, Chromatin, and Protein Acetylation Signaling in Cancer and the Cell Cycle
Targeting Cell Signaling for Cancer Therapy.
Mouse models of brain cancers