Loren Erickson

Erickson, Loren D.

Primary Appointment

Associate Professor, Microbiology, Immunology, and Cancer Biology


  • BS, Biology, Seattle Pacific University
  • PhD, Immunology, The University of Iowa
  • Postdoc, Immunology, Dartmouth Medical School

Contact Information

MR-6 2704
PO Box 801386
Charlottesville, VA 22908
Telephone: 434-982-0756
Fax: 434-924-1221
Email: lde9w@virginia.edu
Website: https://med.virginia.edu/faculty/faculty-listing/lde9w/

Research Disciplines

Cancer Biology, Immunology, Microbiology, Translational Science

Research Interests

Cellular and molecular mechanisms of B lymphocyte function; Genetic susceptibility in systemic lupus erythematosus; Immunotherapeutics in the treatment of B cell disorders

Research Description


- Using mouse genetics to identify the susceptibility factors that control B cell tolerance, differentiation and survival, leading to autoantibody production.

- Defining the mechanisms by which autoimmune susceptibility elicits inflammation and recruitment of innate immune cells in secondary lymphoid organs that affect B cell function.

- Examining helper activity and inflammatory cytokines of human T cells in peripheral blood of SLE patients that affect B cell function.

- Characterizing the regulation and activity in primary mouse T follicular helper cells and T follicular regulatory cells to control B cell responses.

- Defining the signal transduction events through the BCMA cytokine receptor that regulates both T follicular helper cell homeostasis and plasma cell survival in autoimmunity.

- Characterizing the development and persistence of IgE antibodies to airway allergens.

Selected Publications