Welcome to the Derré Lab!

From left to right: Becky Stanhope (Graduate Student), Rachel Ende (Graduate Student), Isabelle Derré (PI) and Maria-Eugenia Cortina (Postdoc).

We study the molecular mechanisms underlying the interaction between pathogens and their mammalian host. In particular, we investigate how the obligate intracellular bacteria Chlamydia trachomatis has evolved to manipulate the eukaryotic cell and establish an intracellular niche favorable for survival and replication. We focus on the interaction between the Chlamydia inclusion and the endoplasmic reticulum. Our approach combines cell biology, molecular biology, microbiology and confocal microscopy techniques together with the newly developed genetic tools for Chlamydia. Please visit our website to learn more about our projects.