Derré Lab

Welcome to the Derré Lab, within the Department of Microbiology, Immunology and Cancer Biology (MIC). We study the molecular mechanisms underlying the interaction between pathogens and their mammalian host. In particular, we investigate how the obligate intracellular bacteria Chlamydia trachomatis has evolved to manipulate the eukaryotic cell and establish an intracellular niche favorable for survival and replication.

We focus on the interaction between the Chlamydia inclusion and the endoplasmic reticulum. Our approach combines cell biology, molecular biology, microbiology and confocal microscopy techniques together with the newly developed genetic tools for Chlamydia.