Selected Publications

Suzich JB, Cliffe AR. Strength in diversity: Understanding the pathways to herpes simplex virus reactivation. Virology. 2018 Jul 14;522:81-91. PubMed PMID: 30014861.

Cliffe AR, Wilson AC.  Restarting Lytic Gene Transcription at the Onset of Herpes Simplex Virus Reactivation., 2016; Journal of virology. 91(2) . PMID: 27807236 | PMCID: PMC5215350

Cliffe AR, Arbuckle JH, Vogel JL, Geden MJ, Rothbart SB, Cusack CL, Strahl BD, Kristie TM, Deshmukh M.  Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation., 2015; Cell host & microbe. 18(6) 649-58. PMID: 26651941 | PMCID: PMC4681005

Gama V, Swahari V, Schafer J, Kole AJ, Evans A, Huang Y, Cliffe A, Golitz B, Sciaky N, Pei XH, Xiong Y, Deshmukh M.  The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells., 2014; Science signaling. 7(334) ra67. PMID: 25028717 | PMCID: PMC4182917

Cliffe AR, Coen DM, Knipe DM.  Kinetics of facultative heterochromatin and polycomb group protein association with the herpes simplex viral genome during establishment of latent infection., 2013; mBio. 4(1) . PMID: 23322639 | PMCID: PMC3551550

Cliffe AR, Garber DA, Knipe DM.  Transcription of the herpes simplex virus latency-associated transcript promotes the formation of facultative heterochromatin on lytic promoters., 2009; Journal of virology. 83(16) 8182-90. PMID: 19515781 | PMCID: PMC2715743

Hancock MH, Cliffe AR, Knipe DM, Smiley JR.  Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells., 2009; Journal of virology. 84(3) 1366-75. PMID: 19939931 | PMCID: PMC2812316

Knipe DM, Cliffe A.  Chromatin control of herpes simplex virus lytic and latent infection., 2008; Nature reviews. Microbiology. 6(3) 211-21. PMID: 18264117

Cliffe AR, Knipe DM.  Herpes simplex virus ICP0 promotes both histone removal and acetylation on viral DNA during lytic infection., 2008; Journal of virology. 82(24) 12030-8. PMID: 18842720 | PMCID: PMC2593313